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Peptide and Protein Drug Analysis

Peptide and Protein Drug Analysis


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About the Book

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design.
Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication.
Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis

  • discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability
  • analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology
  • examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods
  • highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry
  • demonstrates uses of unnatural mutagenesis and combinatorial chemistry
  • explores mass spectrometry, protein sequence, and carbohydrate analysis
  • illustrates bioassays and other new functional analysis methods
  • surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR)
  • addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells
  • reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering
  • and more!
    Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemis

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    Product Details
    • ISBN-13: 9780824778590
    • Publisher: CRC Press
    • Publisher Imprint: Crc Press
    • Height: 260 mm
    • No of Pages: 885
    • Series Title: Drugs and the Pharmaceutical Sciences
    • Weight: 1735 gr
    • ISBN-10: 0824778596
    • Publisher Date: 12 Nov 1999
    • Binding: Hardback
    • Language: English
    • Returnable: N
    • Spine Width: 47 mm
    • Width: 177 mm


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