Трансдермальная рецептура и оценка
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Трансдермальная рецептура и оценка пол&#1080

Трансдермальная рецептура и оценка поли


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About the Book

Целью настоящего исследования является формулирование и оценка подходящей матричной полимерной трансдермальной пленки Ольмесартанского Медоксомила с использованием двух различных полимерных комбинаций, Эвдрагит RL 100 (E RL 100) и Гидроксилпропилметилцеллюлозы (ГПМК). Параметры преформуляции были оценены на предмет их пригодности для формирования трансдермальной полимерной пленки. Трансдермальная полимерная пленка была успешно подготовлена и критически исследована. Параметры оценки, такие как FTIR на совместимость препарата с полимером, Сканирующая электронная микроскопия (СЭМ) фотографии подготовленной пленки были сделаны, чтобы увидеть картину распределения препарата, Физические исследования, включая содержание влаги, поглощение влаги, плоскостность для изучения стабильности рецептур и Исследования In vitro проницаемости проводится в модифицированной диффузионной ячейке Франца с использованием мембраны кожи крыс и целлофановой мембраны. Полученный результат подтверждает, что он соответствует требованиям спецификации или заявленным методам. На основании вышеприведенных наблюдений можно сделать обоснованный вывод о том, что полимеры E RL 100 & HPMC являются наиболее подходящими полимерами для разработки TDDS Ольмесартанского Медоксомила.


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Product Details
  • ISBN-13: 9786203342994
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Sciencia Scripts
  • Height: 229 mm
  • No of Pages: 84
  • Spine Width: 5 mm
  • Width: 152 mm
  • ISBN-10: 6203342998
  • Publisher Date: 19 Feb 2021
  • Binding: Paperback
  • Language: Russian
  • Returnable: N
  • Weight: 186 gr


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