Advances in DNA Repair in Cancer Therapy by Moulay Alaoui-Jamali
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Advances in DNA Repair in Cancer Therapy

Advances in DNA Repair in Cancer Therapy


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International Edition


About the Book

​Preface.- Repair of DNA Interstrand Cross-links Produced by Cancer Chemotherapeutic Drugs.- DNA-PK, a pharmacological target in cancer chemotherapy and
radiotherapy?.- Growth factor receptor signaling, DNA damage response, and cancer cell susceptibility to chemotherapy and relapses.- The relationship between DNA-repair genes, cellular radiosensitivity and the response of tumors and normal tissues to radiotherapy.- Important Roles of ERCC1 in DNA Repair and Targeted Therapy.- The role of BRCA1 and BRCA2 in anticancer drug therapy.- DNA-PK in CLL Chemotherapy.- Poly(ADP) ribose polymerase at the interface of DNA damage signalling and DNA repair.- Cellular protection against the antitumor drug bleomycin.- ATR as a Therapeutic Target.- Telomeres, Telomerase and DNA Damage Response in Cancer Therapy.- RAD51 is a key protein of DNA repair and homologous recombination in humans.- Index.


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Product Details
  • ISBN-13: 9781461447405
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Edition: 2013 ed.
  • Language: English
  • Returnable: Y
  • Spine Width: 23 mm
  • Width: 157 mm
  • ISBN-10: 1461447402
  • Publisher Date: 06 Dec 2012
  • Binding: Hardback
  • Height: 234 mm
  • No of Pages: 312
  • Series Title: Cancer Drug Discovery & Development
  • Weight: 680 gr


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