Androgen-Responsive Genes in Prostate Cancer - Bookswagon UAE
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Androgen-Responsive Genes in Prostate Cancer

Androgen-Responsive Genes in Prostate Cancer


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International Edition


About the Book

​​​Preface.- Roles of androgen receptor coregulators and cell signaling in regulation of androgen-responsive genes.- Selective and classical Androgen Response Elements in androgen-regulated gene expression.- Negative androgen-response elements in androgen target genes.- Chromatin looping and long distance regulation by androgen receptor.- The Functionality of Prostate Cancer Predisposition Risk Regions is revealed by AR Enhancers .- Mechanisms of ARE-independent Gene Activation by the Androgen Receptor in Prostate Cancer Cells: potential targets for better intervention strategies.- Androgen action, Wnt signaling, and prostate tumorigenesis.- Toward Revealing the Complexity of Androgen Responsive Protein and Non-coding Transcripts in Prostate Cancer.- Androgen-Responsive Gene Expression in Prostate Cancer Progression.- Androgen receptor regulated genes in prostate cancer initiation vs metastasis.- Androgen-Independent Induction of Androgen-Responsive Genes By Interleukin-6 Regulation.- The effect of AR overexpression on androgen signaling in prostate cancer.- The expression signature of androgen receptor splice variants and their distinctive transcriptional activities in castration-resistant prostate cancer.- Androgen regulation of the cell cycle in prostate cancer.- Androgen Receptor Signaling Interactions Control Epithelial-Mesenchymal Transition (EMT) in Prostate Cancer Progression.- Androgen receptor regulation of serum response factor signaling in prostate cancer.- Regulation of angiogenesis by androgen-responsive gene EAF2.- The role of miR-21, an androgen-regulated microRNA, in prostate cancer.- Androgen dependent oncogenic activation of ETS transcription factors by recurrent gene fusions in prostate cancer: Biological and Clinical Implications.- Clusterin as a target for treatment of castration-resistant prostate cancer.- Index.
About the Author: The volume editor, Dr. Zhou Wang, is well-noted in the field of prostate cancer and he is theChair for Urological Research at the University of Pittsburgh Medical Center, as well as the co-director of Urological and Prostate Cancer Program at the University of Pittsburgh Cancer Institute.He has also conducted several scientific reviews for several top journals in the area of cancer research.


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Product Details
  • ISBN-13: 9781461461814
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Depth: 25
  • Height: 234 mm
  • No of Pages: 348
  • Series Title: English
  • Sub Title: Regulation, Function and Clinical Applications
  • Width: 157 mm
  • ISBN-10: 1461461812
  • Publisher Date: 16 Feb 2013
  • Binding: Hardback
  • Edition: 1
  • Language: English
  • Returnable: Y
  • Spine Width: 25 mm
  • Weight: 730 gr


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