Angiogenèse tumorale et thérapie anti-angiogénique
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Angiogenèse tumorale et thérapie anti-angiogénique

Angiogenèse tumorale et thérapie anti-angiogénique


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About the Book

La grande majorité des tumeurs primaires sont bénignes et inoffensives pour leur hôte. Les risques de décès causés par une tumeur bénigne sont donc très faibles, voire rares. La plupart des décès liés au cancer sont dus à des métastases. La métastase cancéreuse est un phénomène complexe à plusieurs étapes qui est la propriété exclusive des tumeurs malignes. Au cours de la métastase, les cellules cancéreuses quittent le site de la tumeur initiale (c'est-à-dire la tumeur primaire) et migrent vers d'autres parties du corps via la circulation sanguine ou le système lymphatique. La nouvelle tumeur dans un organe cible éloigné est appelée tumeur secondaire ou métastatique. Dans la plupart des cas, les patients atteints de tumeurs primaires localisées ont un meilleur pronostic que ceux atteints de tumeurs métastatiques. Le processus métastatique et la croissance tumorale dépendent de l'angiogenèse. Ce type d'angiogenèse se caractérise par un développement vasculaire anormal. Dans ce cas, les vaisseaux sanguins créés ne sont pas exactement les mêmes que les vaisseaux sanguins normaux. Ils ne sont pas organisés en veinules, artérioles et capillaires définitifs. Ils sont plus perméables que les vaisseaux normaux. La complexité du processus angiogénique, qui fait intervenir des régulateurs positifs et négatifs, offre un certain nombre de cibles thérapeutiques.


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Product Details
  • ISBN-13: 9786207435937
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 141 gr
  • ISBN-10: 6207435931
  • Publisher Date: 26 Apr 2024
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm


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