1. General Concepts of Pharmacodynamics for Anti-Infective Agents
Johan W. Mouton
2. In Vitro Pharmacodynamic Models to Evaluate Anti-Infective Pharmacodynamics
Warren Rose
3. Animal Models to Evaluate Anti-Infective Pharmacodynamics
Alexander J. Lepak and David R. Andes
4. Pharmacodynamic Issues in Antibiotic Combinations
Zackery P. Bulman, Ryan C. Dillon, Sarith M. Saju, Neang S. Ly, Gauri G. Rao, Phillip J. Bergen, Cornelia B. Landersdorfer, Alan Forrest, Juergen B. Bulitta, and Brian T. Tsuji
5. Methodologies for Protein Binding Determination in Anti-Infective Agents
Jatinder Kaur Mukker, Ravi Shankar Prasad Singh, and Hartmut Derendorf
6. Evaluation of Exposure-Response Relationships Using Clinical Data: Basic Concepts and Applications Sujata M. Bhavnani, Christopher M. Rubino, and Paul G. Ambrose
7. Toxicokinetics and Toxicodynamics of Anti-Infective Agents
David E. Nix
Part II: Pharmacodynamics of Antibacterial Agents
8. Pharmacodynamics of Fluoroquinolones
Ramy Elshaboury, Thomas Dilworth, and John Rotschafer
9. Aminoglycoside Pharmacodynamics
Dana R. Bowers, Amy N. Schilling, and Vincent H. Tam
10. Polymyxin Phar
macokinetics and Pharmacodynamics Soon-Ee Cheah, Jian Li, Phillip J. Bergen, and Roger L. Nation
11. Vancomycin Pharmacodynamics: Optimal vs. Controversial
Ben M. Lomaestro
12. Pharmacodynamics of Lipoglycopeptides
Eric Wenzler, Siyun Liao, and Keith A. Rodvold
Eric Wenzler, Siyun Liao, and Keith A. Rodvold
14. Pharmacodynamics of Macrolides, Azalides, and Ketolides
Wonhee So and David P. Nicolau
Part III: Pharmacodynamics of Non-Antibacterial Agents
15. Antifungal Pharmacokinetics and
Pharmacodynamics William Hope and David R. Andes
16. Pharmacokinetics and Pharmacodynamics of the Tuberculosis Drugs
Aline B. Barth, Eric F. Egelund, and Charles A. Peloquin
17. Pharmacodynamics of Antimalarial Agents
Rahul P. Bakshi and Theresa A. Shapiro
18. Pharmacodynamics of Antiviral Agents
Renee-Claude Mercier, Bernadette Jakeman, and Larry Pineda
19. Pharmacodynamics of Antiretroviral Agents
K
ajal B. Larson and Edward P. Acosta
Part IV: Pharmacodynamic Considerations and Special Populations
20. Implementing a Continuous or Prolonged Infusion Be
ta-Lactam Program in the Hospital Setting Shawn H. MacVane, Nathaniel J. Rhodes, Marc H. Scheetz, and Joseph L. Kuti
21. Pharmacodynamic Considerations in Critically Ill Patients
Mahipal G. Sinnollareddy and Jason A. Roberts
22. Pharmacodynamic Considerations and Special Populations: Pediatrics
Jennifer Le and John S. Bradley
23. Pharmacodynamics and Obesity
Manjunath P. Pai
24. Drug Development Process and Regulatory Science
Evelyn J. Ellis-Grosse and Jogarao Gobburu
25. Antibiotic Stewardship an
d Applications of Pharmacodynamics
