Apoptose dans la paroi de la veine native utilisée pour l'accès à l'hémodialyse
Apoptose dans la paroi de la veine native utilisée pour l'accès à l'hémodialyse

Apoptose dans la paroi de la veine native utilisée pour l'accès à l'hémodialyse


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About the Book

Dans le cadre de l'intérêt croissant pour l'étude de l'apoptose dans les vaisseaux sanguins, cette étude est l'une des premières à évaluer l'apoptose dans les veines natives utilisées pour les fistules artério-veineuses (FAV) pratiquées pour l'hémodialyse. L'objectif de cette étude était d'évaluer l'apoptose dans les veines natives préalablement ponctionnées (groupe d'étude) par rapport aux veines natives non ponctionnées (témoins) chez les patients qui subissent une procédure chirurgicale pour une FVA comme accès à la dialyse. Des échantillons de veines céphaliques ont été prélevés sur 60 patients avant la mise en place d'une FAV. La moitié des échantillons provenait de veines précédemment ponctionnées et l'autre moitié de veines non ponctionnées. Un segment de 1 cm de long a été excisé de la partie distale de la veine céphalique, divisé en deux parties le long de l'axe longitudinal et préparé pour l'analyse immunohistochimique. L'évaluation immunohistochimique et la quantification des signaux ont été utilisées pour évaluer l'expression de Bax, p53, caspase 3 et Bcl-2. L'association que nous avons trouvée entre les veines précédemment ponctionnées et l'apoptose indique le rôle que la ponction veineuse peut jouer dans le développement de l'apoptose. Les patients présentant une apoptose accrue ont montré une augmentation de l'échec de la fistule.


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Product Details
  • ISBN-13: 9786207964024
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 154 gr
  • ISBN-10: 6207964020
  • Publisher Date: 19 Aug 2024
  • Height: 229 mm
  • No of Pages: 64
  • Spine Width: 4 mm
  • Width: 152 mm


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