Brain Slices in Basic and Clinical Research
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Brain Slices in Basic and Clinical Research

Brain Slices in Basic and Clinical Research

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About the Book

Brain Slices in Basic and Clinical Research describes advancements in the field of brain function and dysfunction through use of central nervous system slice preparations. Topics are authored by leading scientists and include the following: Mechanisms of synaptic plasticity as the basis of memory processes Chaos and synaptic variability Brain calcium currents Glutamate receptors Pathophysiology of excitotoxins Cerebral hypoxia-ischemia Neuronal injury Free radicals Optical methods of measuring brain metabolism Voltammetry in brain slices Calcium imaging Patch-clamp recording and application of macromolecules through patch-clamp pipettes in brain slices Intracellular double labeling of various neuronal populations Use of brain slices in teaching neurophysiological methods Most of the topics are published in book format for the first time, and some of the techniques are more fully detailed than in any other book.

Table of Contents:
Advances in Understanding the Mechanisms Underlying Synaptic Plasticity, T. Teyler, I. Cavus, C. Coussens, P. DiScenna, L. Grover, Y. Lee, and Z. Little Chaotic Components of Synaptic Variability in Hippocampal Pathways, P.G. Aitken, S.J. Schiff, and T. Sauer Intrinsic Optical Properties of Brain Slices: Useful Indices of Electrophysiology and Metabolism, T.J. Sick and J.C. LaManna Voltammetry in Brain Slices, J.A. Stamford Imaging of Intracellular Calcium in Hippocampal Slices: Methods, Limitations, and Achievements, M. Segal and J.M. Auerbach Patch-Clamp Recording in Brain Slices, F.A. Edwards Intracellular Application of Macromolecules through Patch Pipettes in Brain Slices, M. Alreja and G.K. Aghajanian Intracellular Double Labeling of Substantia Nigra and Pedunculopontine Neurons in In Vitro Slice Preparation, S.T. Kitai and Y. Kuga The Importance of Temperature Control When Investigating High-Threshold Calcium Currents in Mammalian Neurones, R.H. McAllister-Williams and J.S. Kelly A Neurochemical Approach to Elucidate Metabotropic vs. Ionotropic Glutamate Receptor Activities in Rat Hippocampal Slices, D.D. Schoepp and M.A. Desai Radiotracer Labeling of Brain Slices, G.C. Newman, F.E. Hospod, C.S. Patlak, and H. Qi The Pharmacology of Excitotoxins and Energy Deprivation in Hippocampal Slices, A. Schurr and B.M. Rigor Delayed Neuronal Injury in the Hippocampal Slice, R.-A. Wallis and K.L. Panizzon Gene Expression as an Index of Pathophysiology Associated with Slice Preparation, T.S. Nowak, Jr., Q. Zhou, P.J. Voulalas, and J.M. Sarvey Studies on Anoxic Depolarization, M. Balestrino The Use of Brain Slices in the Study of Free Radical Actions, T.C. Pellmar Using the In Vitro Hippocampal Slice as a Model to Teach Methods in Neurophysiology, S. Veregge


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Product Details
  • ISBN-13: 9780849347603
  • Publisher: Taylor & Francis Inc
  • Publisher Imprint: CRC Press Inc
  • Height: 234 mm
  • No of Pages: 352
  • Width: 156 mm
  • ISBN-10: 0849347602
  • Publisher Date: 13 Apr 1995
  • Binding: Hardback
  • Language: English
  • Weight: 680 gr


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