Caractérisation des systèmes nanostructurés à base de lipides
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Caractérisation des systèmes nanostructurés à base de lipides

Caractérisation des systèmes nanostructurés à base de lipides


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About the Book

Les transporteurs lipidiques nanostructurés sont obtenus à partir d'un mélange de lipides solides et liquides; ce mélange est solide à température ambiante. Les NLC constituent une deuxième génération de nanoparticules lipidiques, qui présentent l'avantage d'améliorer la capacité de chargement des médicaments et les propriétés de libération. L'objectif de ce chapitre est de présenter les approches récentes en matière de sélection du ou des systèmes lipidiques les plus appropriés, les méthodes de caractérisation de leur comportement in vitro et in vivo, ainsi que les techniques actuelles de formulation et de traitement permettant d'obtenir diverses formes de dosage solides. La conception ciblée de nanoparticules pour une charge médicamenteuse efficace et des profils de libération définis n'est toujours pas une procédure de routine, même après 25 ans de recherche sur les nanoparticules à base de lipides. Elle nécessite une connaissance détaillée de l'interaction du médicament avec les composés lipidiques, ainsi que de sa localisation et de sa distribution dans la nanoparticule. Dans le présent travail, les données publiées sur la compatibilité in vitro et in vivo des SLN/NLC ont été examinées, afin d'apporter la preuve d'une biocompatibilité élevée en fonction de la voie d'administration prévue.


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Product Details
  • ISBN-13: 9786207611430
  • Publisher: KS Omniscriptum Publishing
  • Binding: BC
  • Language: fre
  • Returnable: N
  • Weight: 150 gr
  • ISBN-10: 6207611438
  • Publisher Date: 31 May 2024
  • Height: 229 mm
  • No of Pages: 60
  • Spine Width: 4 mm
  • Width: 152 mm


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