Carcinoma de pulmón en no fumadores
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Carcinoma de pulmón en no fumadores

Carcinoma de pulmón en no fumadores


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About the Book

El cáncer de pulmón es una enfermedad con muy mal pronóstico que en todo el mundo produce más de un millón de muertes al año, por delante del cáncer de mama, el de colon y el de próstata juntos.

Está relacionado con el hábito de fumar, pero también puede aparecer en personas sin contacto con los tóxicos del tabaco, y es precisamente en esta subpoblación de pacientes no fumadores en la que se ha observado el mayor avance en los conocimientos de cáncer de pulmón.

El descubrimiento de las mutaciones de EGFR y su tratamiento específico con inhibidores de la tirosina cinasa (erlotinib y gefi tinib) han abierto un camino en la terapéutica del cáncer de pulmón y del cáncer en general que ofrece un importante benefi cio para los pacientes, y una manera distinta de entender la enfermedad a los profesionales sanitarios.

Posteriormente, con el descubrimiento de las translocaciones de ALK y su tratamiento, y de otras alteraciones moleculares, se han ampliado los conocimientos sobre el cáncer de pulmón y se ha roto el paradigma de considerarlo como una única enfermedad.

Sin embargo, no hay que olvidar que la mayoría de los pacientes la presentan sin una alteración molecular específica, por lo que son necesarios mayores esfuerzos para conocer su génesis y así poder tratarla de manera más efectiva.

Esta obra intenta sintetizar los conocimientos actuales sobre el cáncer de pulmón, con especial énfasis en la población de pacientes que pueden obtener un mayor benefi cio si somos capaces de seleccionarlos adecuadamente: aquellos con alteraciones moleculares específicas que producen un efecto de adicción oncogénica.


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Product Details
  • ISBN-13: 9788415340706
  • Publisher: Marge Books
  • Binding: Paperback
  • Language: Spanish
  • Returnable: Y
  • Weight: 385 gr
  • ISBN-10: 8415340702
  • Publisher Date: 20 Dec 2023
  • Height: 240 mm
  • No of Pages: 210
  • Spine Width: 11 mm
  • Width: 170 mm


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