Cell Cycle Regulation and Development in Alphaproteobacteria
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Cell Cycle Regulation and Development in Alphaproteobacteria

Cell Cycle Regulation and Development in Alphaproteobacteria


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Preface

Chapter 1: Towards a Comparative Systems Biology of the Alphaproteobacterial Cell Cycle

Abstract Introduction Comparative genomics of the cell cycle Cell cycle involvement of sncRNAs Towards Comparative Systems Biology of the Cell Cycle Conclusions Bibliography

Chapter 2: Temporal control of promoter activity during the Caulobacter cell cycle.

Early S-phase transcriptional control - DnaA, and its targets - Regulation of DnaA - GcrA, and its targets - Regulation of GcrA Late S-phase transcriptional program - CtrA, and its targets - Regulation of CtrA - Negative regulation by the ancestral virulence regulators, MucR1/2 The G1 phase transcriptional program - CtrA, and its target - Negative regulation of the S-phase promoters by the small CtrA inhibitory protein SciP - TacA, and its targets Transcriptional cascades in cell cycle regulated functional modules - Transcriptional control of flagellar biogenesis - Chemotaxis machinery biogenesis transcriptional control - Pili biogenesis transcriptional control - Transcriptional control of the divisome - Transcriptional control of capsulation - Transcriptional control of holdfast formation and stalk biogenesis Transcriptional reprogramming in response to changing environmental conditions - Alternative Sigma factors and stationary phase regulators - (p)ppGpp - Small regulatory RNAs

Chapter 3: Cell cycle signal transduction and proteolysis in Caulobacter

Abstract Introduction - The two-component signaling paradigm - Cyclic-di-GMP-dependent signaling Two core phosphorylation pathways regulate the Caulobacter cell cycle and development Non-canonical interactions between the DivJ-PleC-DivK and CckA-ChpT-CtrA pathways control polarity and development cdG signaling regulates the Caulobacter cell cycle and polar development - The cell cycle signaling network both generates and is modulated by cdG oscillations - cdG signaling is required for polar morphogenesis Spatial regulation of CckA activity Proteolytic regulation of the Caulobacter cell cycle - AAA+ proteases and adaptor-mediated proteolysis - Cell cycle regulation of CtrA proteolysis - Regulated proteolysis of proteins that modulate CtrA activity - Proteolysis o


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Product Details
  • ISBN-13: 9783030906207
  • Publisher: Springer Nature Switzerland AG
  • Binding: Hardback
  • Language: English
  • Returnable: N
  • Weight: 666 gr
  • ISBN-10: 3030906205
  • Publisher Date: 16 Mar 2022
  • Height: 234 mm
  • No of Pages: 312
  • Spine Width: 19 mm
  • Width: 156 mm


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