Preface: Proceedings of 21st ICCE, Peter Mahaffy.- Introduction to the book, Mei-Hung Chiu, Hsiao-Lin Tuan, Hsin-Kai Wu, Jing-Wen Lin, Chin-Cheng Chou.- Section 1. Globalization and Chemical Education, Mei-Hung Chiu.- Dissemination of achievements in chemical education (research) via EU projects, Anna Kolasa, Iwona Maciejowska.- 2. Polish Education Reform and Resulting Changes in the Process of Chemical Education, Hanna Gulińska.- Section 2. Learning and Conceptual Change in Chemistry, Jing-Wen Lin.- Assessment of Chemistry Anxiety among College Students, Chen Chong Sheau Huey.- Teacher-Student Interactions: The Roles of in-Class Written Questions, Liliana Mammino.- Probing and Fostering Students' Reasoning Abilities with a Cyclic Predict-Observe-Explain Strategy, Jia-Lin Chang, Chiing-Chang Chen, Chia-Hsing Tsai, Yong-Chang Chen, Meng-Hsun Chou, Ling-Chuan Chang.- A Trial of Placement and Embodiment of Images for Chemical Concepts in the Lesson Model of "Surface Active Agent" through SEIC, Haruo Ogawa, Hiroki Fujii.- Section 3. Teaching Chemistry, Hsiao-Lin Tuan.- Chemistry pre-service teachers' mental models of science teaching and learning in Malaysia, Maryam Sulaiman, Zurida Haji Ismail.- Chemistry Teachers Enhance their Knowledge in Contemporary Scientific Areas, Rachel Mamlok-Naaman, Ron Blonder, Avi Hofstein.- Practical Science Activities in Primary Schools in Malaysia, Norita Mohamed, Mashita Abdullah, Zurida Hj Ismail.- Teaching Chemistry Effectively with Engineering Majors: Teaching Beyond the Textbook, Yermesha Kyle; Stephen Bacon; Amber Park; Jameka Griffin; Raicherylon Cummins; Raymond Hooks, Bailu Qian, Hua-Jun Fan.- Problem-Based Learning as an Approach to Teach Cell Potential in Matriculation College, Malaysia, Kai-Li Teh, Nooraida Yakob.- Teaching Catalysis by Means of Enzymes and Microorganisms, Peter Grunwald.- The Application of the SATL in Biochemistry, Suzana B. Golemi.- Section 4. Curriculum, Evaluation, and Assessment in Chemistry Education, Mei-Hung Chiu.- An Alignment Analysis of Junior High School Chemistry Curriculum Standards and City-Wide Exit Exams in China, Hongjia Ma, Gavin W. Fulmer, Ling L. Liang, Xian Chen, Xinlu Li, Yuan Li.- A National Survey of Students' Conceptions and Their Sources of Chemistry in Taiwan: Examples of Chemical Equilibrium and Acids/Bases, Jing-Wen Lin, Mei-Hung Chiu.- The use of electronic media for chemical education research, Francis Burns, David Frank.- Investigation of Tertiary Chemistry Learning Environment in Sabah, Malaysia, Yoon-Fah Laya, Chwee-Hoon Khoob.- The Evaluation of Chemistry Competence for Freshmen at Technology Colleges in Taiwan, Ji-Chyuan Yang, Ching-Yun Hsu, Wen-Jyh Wang, Chia-Hui Tai, Hong-Hsin Huang, Ping-Chih Huang.- Changes in Teachers' Views of Cognitive Apprenticeship for Situated Learning in Developing a Chemistry Laboratory Course, Hui-Jung Chen, Mei-Hung Chiu.- Section 5. E-learning and Innovative Instruction, Hsin-Kai Wu.- Application of Mind Map and MindManager to Improve Students' Competence in Solving Chemistry Problems, Zhen Lu, Zheng Zou, Yitian Zhang.- An Integrated-ICT Assessment for College Students' Performances of Chemical Learning, King-Dow Su.- Academic Performance and Attitude Toward Computer-Aided Instruction in Chemistry, Ronaldo C. Reyes.- Integrating Instant Response System (IRS) as an In-Class Assessment Tool into Undergraduate Chemistry Learning Experience: Student Perceptions and Performance, Tzy-Ling Chen, Yan-Fu Lin, Yi-Lin Liu, Hsiu-Ping Yueh, Horn-Jiunn Sheen, Wei-Jane Lin.- Section 6. Microscale Lab Chemistry, Chin-Cheng Chou.- Aqueous cationic and anionic surfactants for microscale experiments in organic chemistry teaching laboratories, Masayuki Inoue, Yuko Kato, Emi Joguchi, Wataru Banba.- Development of Analytical Method of Gaseous Mixture by Using a Syringe, Takashi Yasuoka.- Microscale Experiments Using a Low-Cost Conductance Meter, Jose H. Bergantin, Jr., Djohn Reb T. Cleofe, Fortunato Sevilla III