Classification histopathologique et système de classement de l'OSCC
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Classification histopathologique et système de classement de l'OSCC

Classification histopathologique et système de classement de l'OSCC


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About the Book

Le classement histologique est utilisé depuis longtemps pour prédire le comportement clinique et le pronostic des OSCC. Il a été introduit pour la première fois en 1920 par Broders, sur la base de la proportion de cellules différenciées par rapport aux cellules indifférenciées/anaplasiques dans l'ensemble de la population de cellules tumorales, et classé en tumeurs hautement/bien, modérément, faiblement différenciées et indifférenciées. Bryne et al ont modifié le système de classification d'Anneroth en émettant l'hypothèse que les caractéristiques morphologiques des fronts invasifs sont importantes pour prédire le comportement clinique et le pronostic d'une tumeur. Son hypothèse était que les cellules tumorales des fronts invasifs de la tumeur sont susceptibles d'être celles qui métastasent, de sorte que leurs caractéristiques sont susceptibles d'être plus prédictives que celles de la masse de la tumeur. Sur la base de diverses caractéristiques moléculaires, des études ultérieures ont également souligné que l'exclusion des parties centrales et superficielles des tumeurs augmenterait le pouvoir pronostique de tout système de classification, car ces dernières zones ne représentent pas le phénotype métastasique. Le système modifié de classification de la malignité de Bryne et al. ne classait que les zones les plus anaplasiques au niveau des fronts invasifs des tumeurs.


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Product Details
  • ISBN-13: 9786205848869
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 100
  • Spine Width: 6 mm
  • Width: 152 mm
  • ISBN-10: 6205848864
  • Publisher Date: 28 Mar 2023
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 209 gr


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