The present book is an attempt of Biochemistry Departments as well as budding clinicians to the need made out in the above paragraph. The main stress of the book is on disease diagnosis for which both clinical findings and the laboratory tests have their own importance (although neither of the two has 1 00% predictability value for the purpose). Thus desired stress has been laid on the clinical presentations of patients. Brief mention of pathophysiological mechanisms should facilitate both grasp of clinical presentations as well as selection of suitable tests for the problems of the patients. The biochemical tests have been discussed in context of the demand of the clinical situation. The reason for the choice of the test has amply been explained. The analytical and theoretical details about the tests have been avoided. At many places relative importance of the clinical features or results of other investigations to the bio-chemical test in a clinical situation has been defined. The objective type questions are meant to highlight certain points of the text. Some of these however provide independent pieces of information. The case histories are meant to illustrate the manner in which the information in a chapter will be required to be used. These are only illustrative and not taken out of the case files of actual patients. About the Author Dr. A.S.Saini formerly Director and Professor and Head Deptt. of Biochemistry Post Graduate Institute of Medical Sciences Rohtak is one of the very senior medical graduates opting for Biochemistry as his career. He guided a large number of MD / PhD Biochemistry students and post graduates of other departments and supervised a large number of ICMR and CSIR projects publishing about 100 research and review papers six of which have been reported as recommended methods in different books. He served as member National Executive Nutrition Society of India and Medical Council of India also as a member of some of their Expert Groups. He was President ofIndian Association of Medical Biochemists for the year 1994-95.Dr. (Mrs.) J. Kaur after graduating and obtaining D.G.O. from Mahatma Gandhi Institute of Medical Sciences Sevagram subsequently opted for Biochemistry as her career. Presently she is working as Reader in Biochemistry at Government Medical College Chandigarh She has about a score of research publications and is trained in Endocrinological and DNA (PCR) techniques and presently her field of interest -is Clinical Endocrinology. She is also a co-author in the Textbook of Biochemistry.