Clinical Research Transformed by Olli S. Miettinen
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Clinical Research Transformed

Clinical Research Transformed


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International Edition


About the Book

Foreword
Preface
Acknowledgements
Essence of Clinical Medicine
Essence of Clinical Research
Clinical Research and Clinical Medicine at present
Clinical Research Transformative of Clinical Medicine

Core Concepts of Epidemiology and Epidemiological Research

The Epidemiological Interface of Gnostic Clinical Research

The Logistic Regression Model

Statistics from the Model's Fitting to Gnostic Data

The Types of Diagnostic Challenge and Needs for Knowledge

Harvesting Experts' Diagnostic Probability Estimates

Objects Design for a Diagnostic Probability Study

Methods Design for a Diagnostic Probability Study

The Bayes' Theorem Framework for Diagnostic Research

Research Focused on Diagnostic Tests

Introduction to Etiognostic Research
Objects Design for an Etiognostic Study
Methods Design for an Etiognostic Study
Introduction to Prognostic Research

Example: Research on 'Hormone Replacement Therapy'

Prognostic Probability Functions from Clinical-trial Data

Non-experimental Intervention-prognostic Studies

Intervention-prognostic Derivative Research

Theory of Medicine Defining the Essential Missions for Clinical Research

Theory of Clinical Research for Its Essential - Gnosis-serving - Missions

Toward Worldwide Scientific Clinical Medicine

Glossary

Appendix 1: What about 'Machine Learning'?

Appendix 2: On Excellence of Epidemiologic Academia

Index



About the Author:

Olli Miettinen was born in Piikkiö, Finland on 31 July 1936. He obtained his MD from the University of Helsinki and the MPH and PhD degrees from the University of Minnesota. He was Professor of Epidemiology and Biostatistics at Harvard School of Public Health from 1974 to 1986, and has been a Professor in the Department of Epidemiology, Biostatistics, and Occupational Health and in the Department of Medicine of the Faculty of Medicine at McGill University since 1985. He is the author of 3 textbooks and a veteran of extensive teaching internationally.

Albert Hofman, is the Stephen B. Kay Family Professor of Public Health and Clinical Epidemiology and Chair, Department of Epidemiology at the Harvard T.H. Chan School of Public Health.

Dr. Hofman received an MD in 1976 from the University of Groningen, and a PhD in 1983 from the Erasmus University Rotterdam. He was appointed in 1981 as an Assistant Professor at the Erasmus University Medical School and was promoted to Associate Professor in 1984. Since 1988 he has been full Professor and Chair in the Department of Epidemiology at the Erasmus Medical Center. In addition, Dr. Hofman has been a Science Director at the Netherlands Institute for Health Sciences since 1992, as well as an adjunct Professor of Epidemiology at our School since 1998, and a Visiting Professor of Clinical Epidemiology since January 2016. Dr. Hofman has an excellent record of teaching, including being the initiator and program director of the Erasmus Summer Program since 1991, and teaching the summer session courses on Fundamentals of Epidemiology and on Study Design in Clinical Epidemiology at Harvard.

Johann Steurer is the Director of the Horten Centre for patient oriented research and knowledge transfer. University of Zürich.


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Product Details
  • ISBN-13: 9783030061753
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Height: 234 mm
  • No of Pages: 302
  • Spine Width: 19 mm
  • Width: 156 mm
  • ISBN-10: 3030061752
  • Publisher Date: 28 Oct 2019
  • Binding: Hardback
  • Language: English
  • Returnable: Y
  • Weight: 684 gr


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