Connectomic Deep Brain Stimulation
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Connectomic Deep Brain Stimulation

Connectomic Deep Brain Stimulation

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About the Book

Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson’s Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more.  This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery.

Table of Contents:
Part I: Deep Brain Stimulation and Connectomics – A Fruitful Marriage? 1. Deep Brain Stimulation – an Introduction 2. The “connectomic revolution” in the field of neuroimaging 3. The mechanism of deep brain stimulation Part II: DBS Imaging Methods 4. DBS Imaging - An Overview 5. DBS Imaging Methods I: Preprocessing 6. DBS Imaging Methods II: Electrode Localization 7. DBS Imaging Methods III: Estimating the electric field and Volume of Tissue Activated 8. DBS Imaging Methods IV: Stereotactic Spaces 9. DBS Imaging Methods IV: Group Analyses Part III: Connectomics in DBS 10. Resting-State functional MRI based Connectivity 11. Diffusion-weighted MRI based Connectivity 12. Normative Connectomes and their use in DBS 13. Investigating Network Effects of DBS with fMRI 14. High-Resolution Resources and Histological Mesh Tractography 15. Using brain lesions to inform connectomic DBS 16. Electrophysiological connectivity measures from DBS-targets in Parkinson’s disease and Dystonia Part IV: Applications of Connectomic DBS 17. Predicting treatment response on a local level 18. Predicting treatment response based on DBS connectivity 19. Connectomic DBS in Parkinson’s Disease, Essential Tremor and Dystonia 20. Connectomic DBS in Major Depression 21. Connectomic DBS in Obsessive Compulsive Disorder 22. Connectomics in the Operation Room 23. Investigating cognitive neuroscience concepts using connectomic DBS 24. Combining invasive and noninvasive neuromodulation techniques via connectomics Part V: Outlook 25. Outlook: Toward Personalized Connectomic Deep Brain Stimulation 26. Whole-brain modelling to predict optimal DBS targeting


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Product Details
  • ISBN-13: 9780128218617
  • Publisher: Elsevier Science Publishing Co Inc
  • Publisher Imprint: Academic Press Inc
  • Height: 235 mm
  • No of Pages: 600
  • Width: 191 mm
  • ISBN-10: 0128218614
  • Publisher Date: 13 Sep 2021
  • Binding: Paperback
  • Language: English
  • Weight: 1180 gr


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