Deferring Development: Setting Aside Cells for Future Use in Development and Evolution

This volume examines cells set aside during development for use later in ontogeny or in adult life. There is no single term for such cells. The cells explored fall within several major categories — stem cells, set-aside cells (in echinoderm larvae), imaginal discs in insects such as Drosophila, meristems (plants), blastemata (regeneration in amphibians), neoblasts (regeneration in planarians). The book compares and contrasts these cell types and the environments (niches) in which they operate with the aim of unravelling any relationships between them, between their activation in development, and in their evolution. Key Features Explores the nature of deferred-use cells in evolutionary and developmental context. Reviews the mechanisms of development of set-aside cells, such as stem cells, meristems, and imaginal discs. Provides phylogenetic overview of different types of deferred-use cells. Compares and contrasts different theories on the origin of deferred-use cells. Related Titles Calegari, F. & C. Waskow, eds. Stem Cells: From Basic Research to Therapy (ISBN 978-1-4822-0775-0) Cabral, J. M. S. & C. L. da Silva, eds. Bioreactors for Stem Cell Expansion and Differentiation (ISBN 978-1-4987-9590-6) Kong, H., A. J. Putnam, & L. B. Schook, eds. Stem Cells and Revascularization Therapies (ISBN 978-1-4398-0323-3) Schaffer, D., J. D. Bronzino, & D. R. Peterson, eds. Stem Cell Engineering: Principles and Practices (ISBN 978-1-4398-7204-8)

Table of Contents:
Section I Deferred-use Cells and Niches. 1. Deferred-Use Cells in Development and Evolution A Life History Perspective. 2. Deferred-Use Molecules and Decision-Making in Development. 3. Coevolution of the Cell Cycle and Deferred-Use Cells. Section II Origin of Deferred-Use Cells and Their Niches: Phylogenetic Approaches. 4. The Early Evolution of Cellular Reprogramming in Animals. 5. Macroalgae as Underexploited Model Systems for Stem Cell Research. 6. Meristems, Stem Cells, and Stem Cell Niches in Vascular Land Plants. 7. Planarian Neoblasts: Nondeferred, Multipurpose Stem Cells for Body Homeostasis, Growth, Degrowth, and Regeneration. 8. Skeletal Muscle Satellite Cells: Adult Stem Cells with Multipotential Capacity. Section III Deferred-Use Cells in Development and Evolution. 9. Sustained Pluripotency Underwrites Extreme Developmental and Reproductive Plasticity. 10. The Coordination of Insect Imaginal Discs and the Regulation and Evolution of Complex Worker Caste Systems of Ants. 11. Evolution of Adaptive Immunity through Set-Aside Cells. 12. The Lack of Human Somatic Set-Aside Cells and Cancer Risks. 13. Microbes: New Actors in the Stem Cell Niche. 14. Stem Cells in a Holobiont: Lessons from Hydra. Subject Index. Systematic Index.