Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases
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Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases

Effects of Omega-3 Fatty Acids on Cognitive Function with Aging, Dementia, and Neurological Diseases


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About the Book

This report is one of several reports focusing on the role of omega-3 fatty acids (FA) in the prevention or treatment of various diseases. This report focuses on the effects of omega-3 FA on cognitive function with aging, dementia, and neurological diseases. Over the past 40 years, an increasing number of physiological functions have been attributed to omega-3 FA, including movement of calcium and other substances into and out of cells; relaxation and contraction of muscles; regulation of clotting and of secretion of substances that include digestive enzymes and hormones; and control of fertility, cell division, and growth. In addition, omega-3 FA may play an important role in brain development and function. Docosahexaneoic acid (DHA; 22:6n-3) is the precursor to a newlydescribed metabolite called 10,17S-docosatriene, which is part of a family of compounds called resolvins. They are released in the brain in response to an ischemic insult and counteract the pro-inflammatory actions of infiltrating leukocytes by blocking interleukin 1-beta-induced NF-kappaB activation and cyclooxygenase-2 expression. DHA also plays a role in retinal rod outer segments by influencing membrane fluidity so as to optimize G protein coupled signaling. The major dietary sources of omega-3 FA in the U.S. population are fish, fish oil, vegetable oils (principally canola and soybean), walnuts, wheat germ, and some dietary supplements. THe following questions are addressed in this study: 1. What is the evidence that omega-3 FA play a role in maintaining cognitive function in normal aging? 2. What is the evidence that omega-3 FA affect the incidence of dementia including Alzheimer's disease? 3. What is the evidence that omega-3 FA are effective in the treatment of dementia including Alzheimer's disease? 4. What is the evidence that omega-3 FA affect the incidence of neurological diseases? 5. What is the evidence that omega-3 FA prevent the progression of multiple sclerosis?


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Product Details
  • ISBN-13: 9781500354527
  • Publisher: Createspace Independent Publishing Platform
  • Publisher Imprint: Createspace Independent Publishing Platform
  • Depth: 13
  • Language: English
  • Returnable: N
  • Spine Width: 8 mm
  • Weight: 412 gr
  • ISBN-10: 150035452X
  • Publisher Date: 29 Jun 2014
  • Binding: Paperback
  • Height: 280 mm
  • No of Pages: 150
  • Series Title: Evidence Report/Technology Assessment
  • Sub Title: Evidence Report/Technology Assessment Number 114
  • Width: 216 mm


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