Effet de la SA et de l'ASA sur la croissance des cancers du col de l'utérus HT3 et HeLa
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Effet de la SA et de l'ASA sur la croissance des cancers du col de l'utérus HT3 et HeLa

Effet de la SA et de l'ASA sur la croissance des cancers du col de l'utérus HT3 et HeLa


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About the Book

Le cancer du col de l'utérus est l'un des cancers qui touchent les femmes dans le monde entier et dont le taux de mortalité est élevé. Le papillomavirus humain (HPV) est le principal facteur de risque d'infection du cancer du col de l'utérus, à l'origine de près de 99 % des cancers du col de l'utérus dans le monde, en dehors d'autres facteurs. Le HPV a réussi à provoquer le cancer du col de l'utérus en augmentant la régulation de la cyclo-oxygénase (COX). La COX est de deux types, la COX-1 et la COX-2, et est présente en petite quantité dans chaque cellule. Elle participe à la régulation de la néoplasie du cancer du col de l'utérus. Cependant, elle est surexprimée en grande quantité dans les cancers du col de l'utérus. L'inhibition pharmacologique de la COX-1 et de la COX-2 réduit la formation de tumeurs, ce qui en fait un outil très important pour la thérapie et la chimioprévention du cancer du col de l'utérus. Les médicaments anti-inflammatoires non stéroïdiens, à savoir l'acide acétylsalicylique et l'acide salicylique, se sont révélés être des inhibiteurs des enzymes cyclo-oxygénases. Ces médicaments ont été utilisés comme antioxydants, antimicrobiens et anti-inflammatoires et pourraient être utilisés comme médicaments antitumoraux dans de nombreuses lignées cellulaires cancéreuses; il est également possible que l'acide acétylsalicylique et l'acide salicylique inhibent l'angiogenèse par l'inhibition de la COX dans le cancer du col de l'utérus.


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Product Details
  • ISBN-13: 9786206675389
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 154 gr
  • ISBN-10: 6206675386
  • Publisher Date: 15 Nov 2023
  • Height: 229 mm
  • No of Pages: 64
  • Spine Width: 4 mm
  • Width: 152 mm


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