Effetto Della Somministrazione Di Leptina Esogena by Mohd Nizam Haron
Effetto Della Somministrazione Di Leptina Esogena

Effetto Della Somministrazione Di Leptina Esogena


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About the Book

La leptina, una proteina di 16 k-Da, ha dimostrato di avere ruoli in diversi processi fisiologici, come la regolazione del peso corporeo e l'assunzione di cibo, la funzione immunitaria, l'ematopoiesi e la riproduzione. L'ipogonadismo ipogonadotropo e l'infertilità sono caratteristiche comuni nei topi ob/ob carenti di leptina. La somministrazione di leptina esogena aumenta il peso dei testicoli e delle vescicole seminali, aumenta il numero di spermatozoi e ripristina la capacità riproduttiva nei topi carenti di leptina. Anche se gli effetti della carenza di leptina sulla riproduzione sono ben riconosciuti, l'effetto della leptina in eccesso sulla funzione riproduttiva maschile in animali non carenti non è chiaro. La quantità e la qualità dello sperma sono state entrambe correlate negativamente con il BMI, e l'indice di frammentazione del DNA è stato trovato per correlare significativamente con il BMI. Il fattore/i coinvolti nelle alterazioni legate all'obesità nella funzione riproduttiva rimane sconosciuto. Poiché la leptinemia è comunemente evidente negli individui obesi, ci siamo chiesti se la leptina potesse essere responsabile della correlazione negativa riportata tra BMI e quantità e qualità dello sperma. Abbiamo quindi esaminato l'effetto della somministrazione di leptina esogena sulla conta e la morfologia dello sperma in ratti adulti normali.


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Product Details
  • ISBN-13: 9786203316551
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edizioni Sapienza
  • Height: 229 mm
  • No of Pages: 100
  • Spine Width: 6 mm
  • Width: 152 mm
  • ISBN-10: 6203316555
  • Publisher Date: 11 Nov 2022
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Weight: 209 gr


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