Electrophysiological Analysis of Synaptic Transmission by Nicholas Graziane
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Electrophysiological Analysis of Synaptic Transmission

Electrophysiological Analysis of Synaptic Transmission


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About the Book

Overview: Electrophysiology: Strength and Limitation

Part One: Basic Concepts

Chapter 1: Extracellular and intracellular recordings

Chapter 2: Electrical theory

Chapter 3: Amplifiers

Chapter 4: Salt environment

Chapter 5: Electrodes

Chapter 6: Spatiotemporal effects of synaptic current

Chapter 7: Perforated patch

Part Two: Recording of synaptic current

Chapter 8: Isolation of synaptic current

Chapter 9: Fast and slow synaptic currents

Chapter 10: Measuring kinetics of synaptic current.

Chapter 11: Measuring presynaptic release probability

Chapter 12: Long-term measurements

Chapter 13: Measuring reversal potentials

Part Three: Basic Experimentations of synaptic transmission

Chapter 14: Amplitude

Chapter 15: Pre vs. post synaptic effect

Chapter 16: Runup and rundown

Chapter 17: Kinetics of synaptic current

Part Four: Experimentations with computational components

Chapter 18: Measurement of a single synapse

Chapter 19: Measurement of silent synapses

Chapter 20: Dendritic patch

Part Five: Experimentations with molecular and visual components

Chapter 21: Electrophysiological and visual tags

Part Six: In vivo Recordings

Chapter 22: Extracellular recordings


About the Author:

Nicholas M. Graziane, Ph.D.

Dr. Graziane obtained his Ph.D. from The State University of New York at Buffalo, and did his first postdoctoral training at Brown University before joining Dr. Dong's laboratory at University of Pittsburgh. He is a well-published electrophysiologist interested in neurocircuits implicated in psychiatric disease with a focus on the electrical properties of the neurons residing within these neurocircuits. His research interests have contributed to Dr. Graziane's 10+ years of experience as an electrophysiologist and have enabled him to successfully train many undergraduate students, graduate students, and junior postdoctoral fellows who have been interested in beginning a career in electrophysiology. Currently, Dr. Graziane's research focuses on synaptic and circuitry mechanisms underlying psychiatric and psychological disorders. He is funded through a National Research Scholar Award (NIH).

Yan Dong, Ph.D.

Dr. Dong became interested in brain function when he was in high school and started his electrophysiological training during college. He received his Ph.D. from the Chicago Medical School, and did his postdoctoral training at Stanford University. He established and supervised his first independent laboratory at Merck and Co. from 2004 to 2006 as a senior scientist. He then joined Washington State University as an assistant professor in the Program of Neuroscience. In 2012, he joined University of Pittsburgh, and is curr

ently an associate professor in the Department of Neuroscience. His research focuses on synaptic and circuitry mechanisms underlying psychiatric

and psychological disorders. His research has been supported by National Institutes of Health (US), Hope Foundation for Depression Research (US), and Humboldt Stiftung (Germany).


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Product Details
  • ISBN-13: 9781493932733
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Edition: 1st ed. 2016
  • Language: English
  • Returnable: Y
  • Spine Width: 18 mm
  • Width: 178 mm
  • ISBN-10: 149393273X
  • Publisher Date: 16 Dec 2015
  • Binding: Hardback
  • Height: 254 mm
  • No of Pages: 263
  • Series Title: Neuromethods
  • Weight: 748 gr


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