Table of Contents
Introduction
Description for the aim of the book and the book contents
Chapter 1
INTRODUCTION TO ENDOCRINOLOGY
1. Introduction. 2. Comprehensive and classical definition of hormones.
3. Hormonal delivery signalling.
3.1. Intracrine signal
3.2. Juxtacrine signalling.
3.3. Paracrine signalling.
3.4. Autocrine signalling.
3.5. Endocrine signalling.
3.6. Protrusions signalling 4. Endocrine glands, location and functions at glance.
4.1. Pituitary gland and the hypothalamus control................................
4.2. Thyroid gland.
4.3. Parathyroid gland. 4.4. Adrenal glands.
4.5. Pineal gland.
4.6. Pancreas.
4.7. Ovaries.
4.8. Testes.
4.9. Secondary endocrine organs.......................................................
5. Update on Ectopic hormone secretion............................................................
6. General characteristics of the endocrine glands.
7. Chemical classification of hormones.
7.1. Peptides, Proteins and Glycoprotein hormones.
7.2. Glycoprotein hormones.
7.3. Steroid hormones.
7.4. Amino-acid derived hormones. 7.5. Fatty acid derivatives hormones (Eicosanoids).
8. Conclusion.
References list
Chapter 2
BIOLOGICAL SYNTHESIS OF HORMONES IN ENDOCRINE CELLS
1. Introduction.
2. Group one: Proteins and polypeptides.
2.1. Synthesis of the Preprohormone.
2.2. Production of the Prohormone.
2.3. Release of the Hormone. 3. Group Two: Amino acid derivatives.
3.1. Synthesis of Adrenaline and noradrenaline (epinephrine, norepinephrine and dopamine).
3.2. Synthesis of Thyroid gland Hormones.
3.2.1. Thyroglobulin.
3.2.2. Glycoprotein role in Thyrocyte.
3.2.3. Synthesis of thyroid hormones in Follicular cells.
4. Group Three: Steroid hormones.
5. Group four: Terpene hormones
6. Sixteen Principal features of hormones
7. Life cycle of the hormone from synthesis to elimination
8. Emerging strategy for hormone/ receptor degradation as a therapy
9. Methods for studing the functions of the endocrine glands
10. Conclusion.
References list
Chapter 3
MECHANISM OF HORMONES SECRETION AND ACTION
1. INTRODUCTION..
2. Mechanism of target cell signalli
