An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
About the Author: Stefan Offermanns is the director of the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany. The Professor of Pharmacology and former director of the Institute of Pharmacology at the University of Heidelberg holds an MD degree from the Free University (FU) Berlin. Professor Offermanns worked as a Post-Doc in Pharmacology in Berlin and at the California Institute of Technology, Pasadena/CA. In 1997, he was appointed group leader at the Institute of Pharmacology of the FU Berlin, then became a Heisenberg Scholar in 1999 before moving on to Heidelberg in 2000. His field of interest includes cellular and biological functions of G-protein-mediated signal transduction processes in the cardiovascular and nervous system, regulation of cellular functions via members of the plexin B family, and the characterization of new G-protein-coupled receptors / G-protein-coupled receptors as pharmacological targets.
Walter Rosenthal is the President of the Friedrich-Schiller-University of Jena, Germany, and former director of Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Leibniz Institute for Molecular Pharmacology and Professor for Molecular Pharmacology at the Charité University Hospital in Berlin. He is a medical doctor by training (Gießen/Germany, London) and held positions at the Universities of Heidelberg, Berlin and Gießen, and at Baylor College of Medicine, Houston/TX. Walter Rosenthal is interested in intracellular protein trafficking, scaffolding proteins, G-protein-coupled receptors, cAMP/PKA-triggered pathways, aquaporins, molecular defects underlying human disease, and pharmacological interference.
