About the Book
A single book that meets multiple requirements of both MBBS 2nd year exam and PG entrance exams.
More content, less pages, handy look, saves a student’s time.
Concise, bulleted format and to-the-point text, easy-to-read during examination.
Simple and lucid language makes the understanding easy.
Separate boxes for summary of laboratory diagnosis and treatment for quick review.
Schematic diagrams are drawn in a user-friendly manner.
More real images keeping in view the image-based MCQs in PG entrances.
Over 600 images and line diagrams and 300 tables and flowcharts incorporated.
Immunology and virology sections fully updated according to the current need.
Recent updated concepts in epidemiology, laboratory diagnosis and treatment have been included.
Advanced and newer topics are covered, such as H1N1, Ebola, Polio eradication, newer bacterial drug resistance mechanisms (ESBL, VRSA, VRE, XDR-TB) automations and molecular methods in microbiology, etc.
Clinical case-based essay questions and MCQs incorporated at the end of each chapter to reinforce students to prepare for future exams. About the Author
Apurba Sankar Sastry MD DNB MNAMS PDCR
Sandhya Bhat K MD DNB MNAMS PDCR
Table of Contents:
Section 1 General Microbiology
1. Introduction and Bacterial Taxonomy 3
2. Morphology and Physiology of Bacteria 9
3. Sterilization and Disinfection 30
4. Culture Media and Culture Methods 43
5. Identification of Bacteria 53
(Conventional methods, Molecular methods and Automations)
6. Bacterial Genetics 65
7. Antimicrobial Agents, Antimicrobial Resistance and Antimicrobial Susceptibility Testing 78
8. Microbial Pathogenicity 87
Section 2 Immunology
9. Immunity (Innate and Acquired) 97
10. Antigen 105
11. Antibody 110
12. Antigen-Antibody Reaction 121
13. Complement 138
14. Structure of Immune System 145
15. Immune Responses: Cell-mediated and Antibody-mediated 162
16. Hypersensitivity 171
17. Autoimmunity 182
18. Immunodeficiency Disorders 187
19. Transplant and Cancer Immunology 193
20. Immunoprophylaxis and Immunohematology 202
Section 3 Systematic Bacteriology
Gram-positive cocci
21. Staphylococcus 211
22. Streptococcus, Enterococcus and Pneumococcus 221
Gram-negative cocci
23. Neisseria and Moraxella 236
Gram-positive bacilli
24. Corynebacterium 243
Contents
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xvi Essentials of Medical Microbiology
25. Bacillus 250
26. Anaerobes (Clostridium and Non-sporing Anaerobes) 256
27. Mycobacteria 271
(M. tuberculosis, Non tuberculous mycobacteria and M. leprae)
28. Miscellaneous Gram-positive Bacilli 292
(Actionomycetes, Listeria, Erysipelothrix and Trophyrema)
Gram-negative bacilli
29. Enterobacteriaceae-I 298
(Escherichia, Shigella, Klebsiella, Proteus, Yersinia and others)
30. Enterobacteriaceae-II: Salmonella 317
31. Vibrio and Aeromonas 328
32. Pseudomonas and Other Non-fermenters 339
33. Haemophilus and HACEK Group 345
34. Bordetella 351
35. Brucella 355
36. Miscellaneous Gram-negative Bacilli 361
(Campylobacter, Helicobacter, Legionella, Pasteurella, Francisella and agent of
Donovaniasis, Rat-bite fever, Bacterial vaginosis)
Other groups of bacteria
37. Spirochetes 371
38. Rickettsiae, Coxiella, Bartonella 388
39. Chlamydiae 397
40. Mycoplasma and Ureaplasma 405
Section 4 Virology
41. General Properties of Viruses 411
DNA viruses
42. Herpesviruses 433
43. Other DNA Viruses 446
(Parvoviridae, Papillomaviridae, Polyomaviridae, Poxviridae, Adenoviridae and Bacteriophages)
RNA viruses
44. Myxoviruses (Orthomyxoviruses and Paramyxoviruses) and Rubella Virus 457
45. Picornaviruses 475
46. Arboviruses 483
47. Rhabdoviruses (Rabies Virus) 496
48. HIV and Other Retroviruses 503
49. Miscellaneous RNA Viruses 517
[Rodent-borne (Hantaviruses, Arenaviruses), Filoviruses (Ebola virus, Marburg virus),
Coronaviruses, Slow viruses, Rotavirus and other agents of viral gastroenteritis and Bornavirus]
Other groups of viruses
50. Hepatitis Viruses 527
51. Oncogenic Viruses 542
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Contents xvii
Section 5 Mycology
52. Medical Mycology 549
Section 6 Applied Microbiology
53. Normal Microbial Flora of Human Body 581
54. Clinical Microbiology (Infective Syndromes) 585
55. Hospital Acquired Infections 606
56. Biomedical Waste Management 612
57. Bacteriology of Water, Milk, Air and Food 615
Annexures
1. Emerging and Re-emerging Infections 625
2. Bioterrorism 627
3. Laboratory Acquired Infections 629
4. Zoonosis 630
Index 631
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xviii Essentials of Medical Microbiology
Further Reading
? Harrison’s Principles of Internal Medicine, 18th Edition
? Gillespie’s Medical Microbiology and Infection at a Glance, 4th Edition
? Bailey & Scott’s Diagnostic Microbiology, 13th Edition
? Koneman’s Color Atlas and Textbook of Diagnostic Microbiology, 6th Edition
? Mackie and McCartney’s Practical Medical Microbiology, 14th Edition
? Prescott’s Microbiology, 9th Edition
? Jawetz Melnick and Adelbergs’ Medical Microbiology, 26th Edition
? Kuby’s Immunology, 7th Edition
? Abbas’ Cellular and Molecular Immunology, 8th Edition
? Stites’ Medical Immunology, 10th Edition
? Robbins & Cotran Pathologic Basis of Disease, 9th Edition
? Topley and Wilson’s Microbiology and Microbial Infections, 10th Edition
? Patrick R Murray’s Medical Microbiology, 7th Edition
? Centers for Disease Control and Prevention, Atlanta, USA
? World Health Organization (WHO)
? National AIDS Control Organisation (NACO), India
? Revised National Tuberculosis Control Programme (RNTCP), India
? National Vector Borne Disease Control Programme (NVBDCP), India
? Various national and international journals and other internet sources
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