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Eficiência Estrutural, Eficiência Metabólica e Monitorização Funcional

Eficiência Estrutural, Eficiência Metabólica e Monitorização Funcional


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About the Book

A nossa compreensão dos mecanismos responsáveis pelo declínio das capacidades mentais humanas que acompanham o envelhecimento tornou-se uma das maiores preocupações da gerontologia moderna. A nossa compreensão da sua estrutura, organização, função e implicação em doenças e mudanças relacionadas com o envelhecimento aumentou igualmente. A mais recente análise global da patogénese do processo de envelhecimento do BG e do cerebelo a nível molecular sugeriu que o envelhecimento resultou num perfil de expressão genética indicativo de uma resposta inflamatória, stress oxidativo, alteração no ADN mitocondrial, perda de homeostasia (equilíbrio dinâmico) dentro e fora do neurónio e redução do apoio neurotrófico em ambas as regiões cerebrais. Trabalhos recentes fornecem uma pista para evitar as perturbações indesejáveis relacionadas com a idade, em primeiro lugar a restrição calórica que retarda o processo de envelhecimento, uma vez que atenua selectivamente a indução de genes que codificam a resposta inflamatória e de stress associada à idade.


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Product Details
  • ISBN-13: 9786205338223
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 72
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 620533822X
  • Publisher Date: 08 Nov 2022
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 168 gr


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