This book presents the current knowledge on the mechanisms by which exercise lowers blood pressure in hypertension and on its effects on the heart and arteries. In addition, it focuses on the optimal exercise protocols, the international consensus on clinical implementation, and the clinical indications for special populations (obese, diabetic etc). It also addresses possible drawbacks of exercise on left ventricular structure and function. Many experts in epidemiology, patophysiology and clinical research have contributed in preparing the chapters, with the main purpose of guiding clinicians in the optimal application of the present knowledge and to stimulate scientists to fill the gaps in knowledge by performing further research.The book is addressed not only to specialists in Hypertension, Internal Medicine, Cardiology, Metabolism, and Nephrology, but also to general practitioners and all healthcare professionals working in the field of rehabilitation medicine.

Professor Palatini received his medical education at the University of Padua, Italy. He worked for 5 years in the Laboratory of Professor Stevo Julius at the University of Michigan (USA), where he received the local Honour. In 2009, he was appointed as Lecturer of the year by the Belgian Hypertension Society; in the same year, he was appointed as a lecturer by the Indian Society of Cardiology and delivered lectures in six Indian towns. He received the Alberto Zanchetti Award of the ESH in 2021.Coordinator of several international and national studies of hypertension and of clinical pharmacology, he serves on the Editorial Board of several International Journals, including Hypertension and the Journal of Hypertension. Prof. Palatini published over 500 original articles and reviews in international journals for a global IF>2600.

Enrico Agabiti-Rosei is Professor Emeritus at University of Brescia, Italy, where he was the Director of the Medical Clinic, and Chairman of both the Hospital Clinical Department of Medicine, and the University Department of Clinical and Experimental Sciences, until the end of 2017. He has been also the Director of the post-graduate School of Internal Medicine. He specialized in Cardiology and Internal Medicine at the University of Pisa and spent few years abroad in prestigious international research centers as Research Fellow or visiting Professor: in Glasgow, GB, at the BP Unit, in Basel, Switzerland, at Kantonsspital, in Cleveland, Ohio, at the Cleveland Clinic. He has received the Peter Sleight Award of the ESH in 2011. Among others, he was Member of the Task Force appointed to write the 2018 ESC/ESH Guidelines for Hypertension. Prof. Agabiti Rosei was Chairman of the WG on Hypertension and the Heart of the ESC and of the ESH, and was also President of the Italian Society of Hypertension (2005-2007) and of the European Society of Hypertension (2015-2017).

Giuseppe Mancia is Emeritus Professor of the University of Milano-Bicocca. He served as Full Professor of Medicine and Director of the Department of Medicine at the San Gerardo Hospital, Monza, Italy. He is President of the European Society of Hypertension (ESH) Foundation and Chairman of the ESH Educational Committee. He has been President of ESH, the International Society of Hypertension, the Italian Society of Hypertension and the European Society of Clinical Investigation. He has received numerous international Awards and Degrees Honoris Causa for his research on hypertension and cardiovascular diseases and has chaired the Task Force of the European Hypertension Guidelines since 2003. He is an highly cited investigator.