Part I: Overview
1. Experimental Models of Cardiovascular Diseases - Overview -
Jae Gyun Oh and Kiyotake Ishikawa
Part II: In Silico Models
2. An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity
Joshua Mayourian, Eric A. Sobie, and Kevin D. Costa
Part III: In Vitro Models
3. Isolation of Atrial and Ventricular Cardiomyocytes for In Vitro Studies
Jelena Plačkic and Jens Kockskämper
4. Cardiomyocyte Differentiation from mouse Embryonic Stem Cells
Adam T Lynch, Silvia Mazzotta, and Stefan Hoppler
5. Cardiomyocyte Differentiation from Human Embryonic Stem Cells
Silvia Mazzotta, Adam T Lynch, and Stefan Hoppler
6. Induction of Human Induced Pluripotent Stem Cells to Cardiomyocytes using Embryoid Bodies
Takeshi Hatani1, Kenji Miki, and Yoshinori Yoshida
7. Measuring Cardiomyocyte Contractility and Calcium Handling In Vitro
Przemek A. Gorski, Changwon Kho, and Jae Gyun Oh
Part IV: Ex Vivo Models
8. Langendorff Perfusion Method as an Ex Vivo Model to Evaluate Heart Function in Rats
Makino Watanabe and Takao Okada
9. Methods for the Preparation of an Excised, Cross-circulated Rat Heart
Koji Obata and Miyako Takaki
10. Optical Action Potential Mapping in Acute Models of Ischemia-reperfusion Injury: Probing the Arrhythmogenic Role of the Mitochondrial Translocator Protein
Zeki Ilkan, Benjamin Strauss, Chiara Campana, and Fadi G. Akar
11. Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies
Irene C. Turnbull, Joshua Mayourian, Jack F. Murphy, Francesca Stillitano,
Delaine K. Ceholski, and Kevin D. Costa
12. Badimon Perfusion Chamber: An Ex Vivo Model of Thrombosis
M. Urooj Zafar, Carlos G. Santos-Gallego, Lina Badimon, and Juan J. Badimon,
Part V: Small Animal Models
13. Ischemic Model of Heart Failure in Rats and Mice
Jiqiu Chen, Delaine K. Ceholski, Irene C. Turnbull, Lifan Liang, and Roger J. Hajjar
14. Conventional Method of Transverse Aortic Constriction in Mice
Jimeen Yoo, Vadim Chepurko, Roger J. Hajjar, and Dongtak Jeong
15. &nbs