Formulazione e valutazione del cerotto transdermico di amlodipina besilato
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Formulazione e valutazione del cerotto transdermico di amlodipina besilato

Formulazione e valutazione del cerotto transdermico di amlodipina besilato


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About the Book

Gli studi di preformulazione riguardano la descrizione, la solubilità e il punto di fusione del farmaco, che sono risultati comparabili con lo standard. Sulla base di tutti gli studi di preformulazione di cui sopra, il farmaco è risultato adatto per la formulazione transdermica. Sulla base di tutti questi fattori, il sistema di somministrazione transdermica F5 ha avuto una maggiore percentuale di rilascio di farmaco. La formulazione F5 mostra un migliore rilascio prolungato fino a 24 ore rispetto alle altre formulazioni. Si è quindi concluso che la formulazione F5, preparata utilizzando Eudragit RS100 e HPMC, è la migliore per il controllo del rilascio del farmaco fino a 24 ore. Tuttavia, la migliore formulazione F-5 segue la cinetica del primo ordine e il meccanismo di diffusione. I risultati del presente studio hanno incoraggiato l'utilizzo di questa formulazione come sistema di rilascio controllato del farmaco e la possibilità di ridurre al minimo la frequenza di somministrazione.


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Product Details
  • ISBN-13: 9786205853870
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edizioni Sapienza
  • Height: 229 mm
  • No of Pages: 72
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6205853876
  • Publisher Date: 29 Mar 2023
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Weight: 168 gr


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Formulazione e valutazione del cerotto transdermico di amlodipina besilato
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