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Functional Ultrastructure

Functional Ultrastructure


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International Edition


About the Book

ToC of the 2nd edition: (ToC of the 3rd edition tba; will be extended with chapters on ear cells, clara cells, 3D REM microscopy, etc; all chapters will be revised and updated);

The Cell.- Structural Organisation of a Mammalian Cell.- Architecture of the Cell Nucleus.- Cytochemical Detection of Ribonucleoproteins.- Nuclear Lamina.- Detection of Sites of NA Replication and of Interphase Chromosome domains.- Nucleolus.- Changes of the Nucleolar Architecture.- Detection of Sites of RNA Synthesis.- Nuclear Pore Complexes.- Nuclear Pore Complexes: Structural Changes as Monitored by Time-Lapse Atomic Force Microscopy.- Mitosis and Cell Division.- Apoptosis.- Viral Inclusions.- Secretory Pathway of Pancreatic Acinar Cells.- Endomembrane System of Dinoflagellates.- Ribosomes, Rough Endoplasmic Reticulum.- Nuclear Envelope and Rough Endoplasmic Reticulum.- Annulate Lamellae.- Rough Endoplasmic Reticulum: Site of Protein Translocation and Initiation of Protein N-Glycosylation.- Oligosaccharide Trimming, Reglucosylation, and Protein Quality Control in the Rough Endoplasmic Reticulum.- Rough Endoplasmic Reticulum: Storage Site of Aggregates of Misfolded Glycoproteins.- Russell Bodies and Aggresomes Represent Different Types of Protein Inclusion Bodies.- Smooth Endoplasmic Reticulum.- Proliferation of the Smooth Endoplasmic Reticulum.- Pre-Golgi Intermediates.- Pre-Golgi Intermediates: Oligosaccharide Trimming and Protein Quality control.- Golgi Apparatus: A Main Crossroads Along Secretory Pathways.- Protein Secretion Visualised by Immunoelectron Microscopy.- Protein N-Glycosylation: Oligosaccharide Trimming in the Golgi Apparatus and Pre-Golgi Intermediates.- Golgo Apparatus: Site of Maturation of Aspara Gine-Linked Oligo Saccharides.- Cell Type-Related Variations in the Topography of Golgi Apparatus Glycosylation Reactions.- Cell Type-Related Differences in Oligosaccharide Structure.- Topography of Biosynthesis of Serine/Threonine-Linked Oligosaccharides.- Golgi Apparatus and TGN - Structural Considerations.- Golgi Apparatus and TGN - Secretion and Endocytosis.- Golgi Apparatus, TGN and Trans Golgi-ER.- Golgi Apparatus, TGN and Trans Golgi-ER: Tilt Series.- Structure of the TGN.- Brefeldin A-Induced Golgi Apparatus Disassembly.- Brefeldin A-Treatment: Tubulation of Golgi Apparatus and Endosomes.- Brefeldin A-Treatment: Effect on Retrograde Transport of Internalised WGA.- Brefeldin A-Treatment: Transitional ER-Elements and Pre-Golgi Intermediates.- Heat Shock Response of the Golgi Apparatus.- Golgi Apparatus Changes Upon ATP-Depletion and ATP-Replenishment.- Secretory Granules.- Secretory Granule Types.- Goblet Cell - Compound Exocytosis.- Receptor-Mediated Endocytosis Via Clathrin-Coated Vesicles and Virus Endocytosis.- Endosomes and Endocytic Pathways.- Endocytic Trans Golgi Network and Retrograde Traffic into the Golgi Apparatus.- Tubular Pericentriolar Endosomes.- Langerhans Cells and Birbeck Granules: Antigen Presenting Dendritic Cells of the Epidermis.- Caveolae.- Fluid-Phase Endocytosis and Phagocytosis.- Lysosomes.- Lysosomes: Localisation of Acid Phosphatase, Lamp and Polylactosamine.- I-Cell Disease.- Gaucher's disease.- Fabry's Disease.- GM2 Gangliosidoses.- Farber's Disease.- Wolman's Disease.- Glycogenosis Type II.- Cystinosis.- Autophagy: Limited Self-Digestion.- Pexophagy: Autophagy of Peroxisomes.- Mitochondria: Crista and Tubulus Types.- Abnormalities of Mitochondria.- Peroxisomes: Multitalented Organelles.- Peroxisome Biogenesis.- Peroxisomes: Adaptive Changes.- Peroxisomal Disorders.- Glycogen.- Glycogenosis Type I.- Erythropoietic Protoporphyria.- Cytocentre, Centrosome, and Microtubules.- Effects of Microtubule Disruption.- Actin Filaments.- Intermediate Filaments.- Mallory Bodies.- The Plasma Membrane.- Cells in Culture.- Brush Cell.- Glycocalyx (Cell Coat).- Glycocalyx: Cell Type Specificity and Domains.- Glycocalyx Changes in Tumours.- Junctional Complex.- Tight Junctions and Gap Jun
About the Author:

Professor Margit Pavelka, MD

Studies in Medicine at the University of Vienna.

Medical training at the Vienna Hospital "Rudolfstiftung"

and at the Vienna General Hospital; specialization in Internal Medicine

Resident at the Institute of Micromorphology and

Electron Microscopy, University of Vienna; specialization in the fields of electron microscopy, cytochemistry, cytology and ultrastructural histology. Habilitation in Histology and Embryology

Professor of Histology and Embryology at the Leopold Franzens University of Innsbruck and Medical University of Vienna. Head of the Center for Anatomy and Cell Biology at the Medical University of Vienna. Emerita Professor since October 2013

Professor Jürgen Roth, MD, PhD, MD hon.

Studies in Medicine, Friedrich-Schiller-University, Jena

Resident, Institute of Pathology, Friedrich-Schiller-University, Jena

Habilitation and University Docent in Pathology, Friedrich-Schiller-University, Jena

Research Associate, Department of Morphology, University of Geneva

Associate Professor of Cell Biology, Biocenter, University of Basel

Professor of Cell and Molecular Pathology, University of Zurich

Distinguished Professor, Yonsei University Graduate School, Seoul

Emeritus Professor, University of Zurich, since 2009

Editor-in-Chief of Histochemistry and Cell Biology

In 2013, The Journal of Cell Biology named Jürgen Roth: Immunogold master


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Product Details
  • ISBN-13: 9783709120002
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Edition: 0003-Softcover Repri
  • Language: English
  • Returnable: Y
  • Spine Width: 22 mm
  • Weight: 997 gr
  • ISBN-10: 3709120004
  • Publisher Date: 01 Nov 2016
  • Binding: Paperback
  • Height: 279 mm
  • No of Pages: 402
  • Series Title: English
  • Sub Title: Atlas of Tissue Biology and Pathology
  • Width: 210 mm


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