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Glycoscience and Microbial Adhesion

Glycoscience and Microbial Adhesion


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About the Book

bacterial carbohydrate recognition are conveyed, covering Gram-positive as well as Gram-negative bacteria, in Chapter 4 Streptococci and Staphylococci, and in Chapter 5, carbohydrate binding specificities of Helicobacter pylori. In Chapter 6, "Bitter sweetness of complexity," the collected reflections on mic- bial adhesion are expanded by a perspective on a broader impact of glycosylation on cellular adhesion, motility and regulatory processes, paralleling the complexity of N-glycan structures on cell surfaces. It highlights particularly how structural details of N-glycans have been causally related to pathological scenarios, with a focus on (1,6)-N-acetylglucosaminyltransferase. In the final chapter, biofilm formation is reviewed, covering knowledge about structure and biosynthesis of polysaccharide intercellular adhesins (PIAs) which are central to biofilm formation. This comprehensive chapter explains all PIA-related principles of medical device-associated infections. It is our hope, that this collection of expert articles, ranging from structural ch- istry and structural biology to biochemistry and medicine, will be a stimulation and motivation for our colleagues in the life sciences. At the same time, we hope that these reflections on microbial adhesion will awake interest in and promote und- standing of the complex processes associated with the glycocalyx and the multif- eted interactions between the host cell and its "guest," as well as the biological consequences resulting from this mutual interplay.


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Product Details
  • ISBN-13: 9783642013034
  • Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
  • Binding: Hardback
  • Edition: 1
  • Language: English
  • Returnable: Y
  • Spine Width: 18 mm
  • Weight: 508 gr
  • ISBN-10: 3642013031
  • Publisher Date: 26 Jun 2009
  • Depth: 13
  • Height: 239 mm
  • No of Pages: 186
  • Series Title: Topics in Current Chemistry
  • Volume: 288
  • Width: 160 mm


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