About the Book
Because dermatology is a complex visual specialty that mixes medical and surgical approaches to management, trainees need fast access to a wide range of material. This concise new reference uses tables, algorithms, protocols, guidelines, and staging and scoring systems to present succinct guidance on best-practice patient care. Structured around three components -- medical, surgical, and pharmacological -- the book consolidates the core Board exam information residents most often look up. Handbook of Dermatology: A Practical Manual was road-tested as it was developed to ensure usefulness for dermatology residents, dermatologists, and family physicians.
Table of Contents:
Preface, xi Dedication, xii
Abbreviations, xiii
Part 1 General Dermatology
Work-up Quick Reference, 3
Direct immunofl uorescence – where to biopsy?, 3
False positive/negative DIFs, 4
Biopsy for GVHD, 4
The Dermatologic Differential Algorithm, 4
Alopecia Work-Up, 5
Associations, 5
Cicatricial or non-cicatricial?, 5
Aphthosis Classifi cation and Workup, 9
Morphologic classifi cation, 9
Classifi cation by cause, 9
Work-up for complex apthae, 9
Treatment, 9
Amyloidoses, 10
Xanthomas, 11
Hyperlipoproteinemias: Fredrickson Classifi cation, 12
Histiocytosis, 13
Lupus Erythematosus, 17
Systemic lupus erythematosus criteria (4 of 11), 17
Acute cutaneous lupus erythematosus, 17
Subacute cutaneous lupus erythematosus, 17
Chronic cutaneous lupus erythematosus, 17
Autoantibody sensitivities and specifi cities, 18
Antinuclear Antibodies, 20
Autoantibodies in Connective Tissue Diseases, 21
Vasculitis, 22
Treatment of ANCA-associated vasculitis, 22
Anti-neutrophil cytoplasmic antibody, 23
Small vessel vasculitis, 24
Medium (+/- small) vessel vasculitis, 26
Large vessel vasculitis, 27
Cryoglobulinemia, 28
CTCL Classifi cation, 29
Mycosis fungoides variants, 29
MF (TNMB) staging, 31
MF treatment algorithm, 32
Cutaneous B-cell Lymphoma, 33
Leukemia cutis, 33
Monoclonal Gammopathies, 34
Melanoma – Classifi cation, 35
Breslow depth, 36
Melanoma – staging and survival, 36
Melanoma – treatment guidelines, 37
Infectious Disease, 39
Viruses and diseases, 39
Human papillomavirus, 41
Other viral diseases, 42
Mycoses, 45
Vector-borne diseases, 52
Creatures in dermatology, 58
Immunology, 63
Complement, 63
Complement defi ciencies, 64
Angioedema and complement levels, 64
Th profiles, 65
Bullous Disorders, 65
Intracorneal/subcorneal, 65
Intraepidermal blisters, 66
Suprabasilar blisters, 66
Subepidermal with little infl ammation, 66
Subepidermal with lymphocytes, 67
Subepidermal with eosinophils, 67
Subepidermal with neutrophils, 67
Subepidermal with mast cells, 68
Epidermolysis bullosa, 68
Major bullous diseases – clinicopathologic fi ndings, 71
Glands, 75
Disorders or Drugs Associated with Skeletal, Ocular, and/or Nail Findings, 77
Dermatoses of Pregnancy, 88
Neonatal Vesiculopustular Eruptions, 90
Genital Ulcers, 95
Common Contact Allergens, 96
Features suggestive of specifi c irritant/toxin, 100
Plants and dermatoses, 100
Vitamin Defi ciencies/Hypervitaminoses, 103
Genodermatoses, 107
Gene list, 107
Chromosome abnormalities, 133
Tumors, 134
Disorders of cornifi cation, 136
Disorders of hair, nail, ectoderm, 139
Tumor syndromes, 144
Disorders of connective tissue, 146
Disorders of metabolism, 149
Disorders of pigmentation, 154
Disorders of vascularization, 156
Immunodefi ciency syndromes, 159
Miscellaneous, 162
Dermoscopy, 163
Pathology, 165
Histochemical staining, 165
Immunohistochemical staining, 167
Pathologic bodies, 170
Other derm path buzzwords, patterns, DDx, 175
Part 2 Surgery
Surgical Margins Guidelines, 183
Indications for Mohs micrographic surgery, 183
Guideline for Prophylactic Antibiotics, 184
Algorithm for antibiotic prophylaxis, 185
Guideline for Prophylactic Antivirals, 186
Anesthetics, 186
Dose calculation, 186
Tumescent anesthesia, 186
Topical anesthetic, 187
Adverse reaction to local anesthetics, 187
Local anesthetic, 188
Nerve blocks, 189
Surgical Anatomy, 189
Anatomy of the face, 189
Anatomy of the nail, 193
Danger zones in surgery, 194
Dermatomal distribution of sensory nerves, 196
Anatomy of the lower extremity venous system, 197
Cutaneous Reconstruction, 198
Undermining depths in reconstruction, 199
Dangerzone of the neck: Erbs point, 196
Second intention, 199
Simple linear closure, 200
Transposition fl ap, 201
Advancement fl ap, 204
Interpolation fl ap, 206
Rotation fl ap, 207
Skin graft, 208
Sutures, 210
Absorbable, 210
Non-absorbable, 211
Suture removal time, 212
Electrosurgery, 212
Wound Healing, 212
Wound dressing, 213
Antiseptic Scrubs, 214
Lasers, 216
Laser principles, 217
Thermal relaxation time, 217
Laser treatment of tattoo pigment, 218
Photoinduced eye injury, 218
Photodynamic Therapy, 220
Basic principles, 220
Applications, 220
Photosensitizer properties and options, 220
UV Spectrum, 222
UV Protection Measurements, 223
UV Associations/Specifi cities, 223
Glogau Wrinkle Scale, 224
Fitzpatrick Skin Type, 224
Peeling Agents, 224
TCA peel, 225
TCA peel frost level, 225
Jessner solution, 225
Baker-Gordon phenol, 226
Cook total body peel, 226
Pre-peel prep, 226
Post-peel wound care, 226
Botulinum Toxin, 226
Botox injection sites, 227
Fillers, 229
Sclerotherapy, 234
Determine vessel size using needle gauge, 236
Recommended maximum effective concentration of sclerosant to minimize side effects, 236
Part 3 Drugs and Therapies
Medication Quick Reference, 239
Topical steroids, 239
Non-steroidals, 240
Commonly used drugs in dermatology, 240
Systemic Medications, 243
Antimalarials, 243
Immunosuppressive agents, 244
Systemic retinoids, 246
Biologics, 247
General Reference, 249
Metric measurements, 249
Dosage calculation, 249
Drug dispensing and absorption, 249
Corticosteroid, 249
Acne – Topical, 250
Antibiotics, 250
Keratolytics, 250
Acne – Systemic, 251
Antibiotics, 251
Retinoids, 252
Others, 252
Alopecia, 252
Analgesics, 252
Anesthetics – Topical, 253
Antibiotics, 253
Topical/Antiseptic, 253
Systemic, 254
Antibiotic preoperative prophylaxis, see p. 184
Antibiotic regimens, 255
STDs, 257
Antifungals, 257
Topical, 257
Systemic, 258
Antifungal regimens, 260
Antiparasitics, 261
Antivirals, 262
For HSV labialis – topical agents, 262
For HSV 1 or 2 – oral agents, 262
For HSV disseminated disease, 262
For herpes zoster/VZV, 262
For genital warts, 263
For verruca vulgaris, 263
For molluscum, 263
Antihistamines, 263
Sedating, 263
Non-sedating, 264
H2-blockers, 264
Antipruritic, 264
Topical, 264
Oral, 264
Bleaching Agents/Depigmenting Agents, 265
Topical Chemotherapy, 266
Actinic keratoses (AK), 266
Basal cell carcinoma (BCC) – superfi cial BCC, 266
CTCL, 266
Topical agents, 266
Oral agent, 266
Other agent, 267
Psoriasis, 267
Topical agents, 267
Tar, 267
Systemic agents, 267
Seborrheic Dermatitis, 268
Hypertrichosis, 268
Hyperhidrosis, 268
Wound Care, 269
Vitamins/Nutritional Supplements, 269
Miscellaneous Meds, 269
Cytochrome P-450 Interactions, 270
Pregnancy Categories of Commonly Used Dermatologic Agents, 272
Common Dermatologic Drugs and Teratogenic Effects, 273
Dermatologic Drugs Reportedly Associated with Contraceptive Failure, 273
Drug Eruptions, 274
Chemotherapeutic Agents and Skin Changes, 277
Antidote to extravasation of chemotherapeutic agents, 279
UV Light Treatment, 279
UVA/UVB dosing, 279
NBUVB dosing, 280
PUVA, 280
Washington University Dermatology Toxic Epidermal Necrolysis (TEN) Protocol, 282
Diagnosis of TEN, 282
Triage algorithm for TEN patients, 283
Treatment for all TEN patients, 283
Index, 287
Color plate section can be found facing page 208