Handbook of Human Molecular Evolution by Hildegard Kehrer-Sawatzki
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Handbook of Human Molecular Evolution

Handbook of Human Molecular Evolution


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About the Book

Dieses Referenzwerk ist eine zielgruppenorientierte Aufbereitung des Themas und umfasst nahezu 300 Abhandlungen zur Molekularevolution namhafter Experten. Es werden sowohl Grundlagen vermittelt, als auch Fragen der Populationsgenetik und die genetisch bedingte Anfälligkeit für Krankheiten näher erläutert.
About the Author:

David N. Cooper has been Professor of Human Molecular Genetics at Cardiff University since 1996. His research interests focus largely on molecular mechanisms of mutagenesis and genotype-phenotype relationships in a variety of different inherited disorders, population genetics, gene expression, cancer genetics, growth hormone genetics, and molecular evolution. He has written or co-authored Human Gene Mutation (1993), The Molecular Genetics of Haemostasis and Its Inherited Disorders (1994), Venous Thrombosis: From Genes to Clinical Medicine (1997), Human Gene Evolution (1999) and The Molecular Genetics of Lung Cancer (2005). He has also co-edited The Functional Analysis of the Human Genome (1995), Gene Therapy (1996), Neurofibromatosis Type 1: From Genotype to Phenotype (1998) and Fascioscapulohumeral Muscular Dystrophy: Clinical Medicine and Molecular Cell Biology (2004). He acted as Editor-in-Chief of the Nature Encyclopedia of the Human Genome (2003) and is currently Editor of the Genetics & Disease section of the Wiley Encyclopedia of Life Sciences. He has been European Editor of the journal Human Genetics since 1997 and Curator of the Human Gene Mutation Database (www.hgmd.org) since 1996.

Hildegard Kehrer Sawatzki is a Senior Research Fellow in the Institute of Human Genetics, University of Ulm, Germany where she has been a group leader since 2000. She has published extensively in the field of molecular medicine and molecular evolution. Alongside her long-term work on the tumour predisposition syndrome, type 1 neurofibromatosis, she has developed a keen interest in the comparative analysis of the human, chimpanzee and macaque genomes in order to identify inter-species genetic differences, particularly those which are human-specific. She has characterized, at the molecular level, the microscopically-visible chromosomal differences between human and chimpanzee known as pericentric inversions. In addition, she has performed detailed genomic comparisons which have contributed to the identification of the hundreds of small submicroscopic inversions, insertions, deletions and copy number differences that are largely responsible for the genetic divergence of the primates. In 2007, she received the Merckle Research Prize for her work on evolutionary and disease-associated chromosomal breakpoints.
David Cooper and Hildegard Kehrer-Sawatzki are the ELS section editors for Genetics & Disease and Evolution & Diversity of Life, respectively.


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Product Details
  • ISBN-13: 9780470517468
  • Publisher: Wiley
  • Publisher Imprint: Wiley
  • Depth: 1.25
  • Language: English
  • Returnable: Y
  • Spine Width: 132 mm
  • Width: 239 mm
  • ISBN-10: 0470517468
  • Publisher Date: 01 Oct 2008
  • Binding: Hardback
  • Height: 305 mm
  • No of Pages: 1744
  • Series Title: English
  • Weight: 5237 gr


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