Human Monoclonal Antibodies Book by Michael Steinitz
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Human Monoclonal Antibodies

Human Monoclonal Antibodies


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About the Book

Dedication...Preface...Table of Contents...Contributing Authors...
1. Human Monocolonal Antibodies: The Benefits of HumanizationHerman Waldmann
2. Cancer Immunotherapy: The Dawn of Antibody CocktailsIlaria Marrocco, Donatella Romaniello, and Yosef Yarden
3. IgM Natural Autoantibodies in Physiology and the Treatment of DiseaseMahboobeh Fereidan-Esfahani, Tarek Nayfeh, Arthur Warrington, Charles L. Howe, and Moses Rodriguez
4. Monoclonal Antibodies for the Treatment of Melanoma: Present and Future StrategiesMadhuri Bhandaru and Anand Rotte
5. An Efficient Method to generate Monoclonal Antibodies from Human B CellsJenna J. Guthmiller, Haley L. Dugan, Karlynn E. Neu, Linda Yu-Ling Lan, and Patrick C. Wilson
6. Isolation of Antigen-Specific, antibody-Secreting Cells using a Chip-Based Immunospot ArrayHiroyuki Kishi, Tatsuhiko Ozawa, Hiroshi Hamana, Eiji Kobayashi, and Atsushi Muraguchi
7. Purification of Human Monoclonal antibodies and Their FragmentsNicole Ulmer, Sebastian Vigg, Thomas Müller-Späth, and Massimo Morbidelli
8. One-Tube Multicolor Flow Cytometry Assay (OTMA) for Comprehensive Immunophenotyping of Peripheral BloodAnna-Jasmina Donaubauer, Paul F. Rühle, Ina Becker, Rainer Fietkau, Udo S. Gaipl, and Benjamin Frey
9. Humanization and Simultaneous Optimization of Monoclonal AntibodyT. Kuramochi, T. Igawa, H. Tsunoda, and K. Hattori
10. Antibody Fragments Humanization: Beginning with the End in MindNicolas Aubrey and Philippe Billiald
11. Antigen-Specific Human Monoclonal Antibodies from Transgenic MiceSusana Magadán Mompó and África González-Fernández
12. Refining the Quality of Monoclonal Antibodies: Grafting Unique Peptide-Binding Site in the Fab FrameworkJeremy D. King and John C. Williams
13. Basic Procedures for Detection and Cytotoxicity of Chimeric Antigen ReceptorsKeichiro Mihara, Tetsumi Yoshida, and Joyeeta Bhattacharyya
14. Rapid Chimerization of AntibodiesKoji Hashimoto, Kohei Kurosawa, Hidetaka Seo, and Kunihiro Ohta
15. Phage Display Technology for Human Monoclonal AntibodiesDal Ferro Marco, Rizzo Serena, Rizzo Emanuela, Marano Francesca, Luisis Immacoloata, Tarasiuk Olga, and Daniele Sblattero
16. Recombinant Antibody Selections by Combining Phage and Yeast DisplayFortunato Ferrara, Maria Felicia Soluri, and Daniele Sblattero
17. Epitope Mapping via Phage Display from Single Gene LibrariesViola Fühner, Philip Alexander Heine, Kilian Zilkens, Doris Meier, Kristian Daniel Ralph Roth, Gustavo Marçal Schmidt Garcia Moreira, Michael Hust, and Giulio Russo
18. A High-Throughput Magnetic Nanoparticle Based Semi-Automated Antibody Phage Display BiopanningAngela Chiew Wen Ch'ng, Azimah Ahmad, Zoltán Konthur, and Theam Soon Lim
19. A Binding Potency Assay for Pritumumab and Ecto-Domain Vimentin Ivan Babic, Santosh Kesari, and Mark C. Glossy
20. A Method to Detect the Binding of Hyper-Glycosylated Fragment Crystallizable (Fc) Region of Human IgG1 to Glycan ReceptorsPatricia Blundell and Richard Pleass
21. A Cell-Based Reporter Assay Measuring the Activation of Fc Gamma Receptors Induced by Therapeutic Monoclonal AntibodiesMichihiko Aoyama, Minoru Tada, and Akiko Ishii-Watabe
22. "BIClonals" Production of Bispecific Antibodi


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Product Details
  • ISBN-13: 9781493989577
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Height: 254 mm
  • No of Pages: 483
  • Series Title: Methods in Molecular Biology
  • Sub Title: Methods and Protocols
  • Width: 178 mm
  • ISBN-10: 149398957X
  • Publisher Date: 12 Dec 2018
  • Binding: Hardback
  • Language: English
  • Returnable: Y
  • Spine Width: 27 mm
  • Weight: 1128 gr


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