About the Book
Written by more than 40 experts in neurology, neurosurgery, internal medicine, paediatrics, infectious diseases, epidemiology, virology, and the basic neurosciences, this book provides coverage of all aspects of CNS infections, ranging from molecular pathogenesis to diagnosis, therapy, and prevention. Ten major sections of the book cover all viral, bacterial, fungal, and protozoal infections of the CNS, as well as infections caused by rarer pathogens such as mycoplasmas, slow viruses, and helminths. A syndrome-oriented approach is emphasized, but specific diseases such as HIV infections, tetanus, neurosyphilis, and Lyme disease receive separate coverage. The contributors provide information on the history, epidemiology, etiology, pathogenesis and pathophysiology, pathology, clinical manifestations, diagnosis, therapy, and prevention of each syndrome or disease. Concluding chapters provide state-of-the-art coverage of two major diagnostic modalities - evaluation of the cerebrospinal fluid and neurodiagnostic imaging by computerized tomography and magnetic resonance imaging.
Tables, drawings and photographs complement and clarify the text, and a bibliography lists both classic papers and recent (1985-1990) references.
Table of Contents:
Part 1 Viral infections of the central nervous system and related disorders: pathogenesis and pathophysiology of viral infections of the central nervous system, M. Schlitt et al; viral meningitis and the aseptic meningitis syndrom, H.A. Rotbart; encephalitis caused by herpesviruses, including B virus, R.J. Whitley and M. Schlitt; arthropod-borne encephalitides, R.J. Whitley; meningitis and encephalitis caused by mumps virus, J.W. Gnann, Jr et al; slow viral infections of the human nervous system, D.M. Asher; perinatal viral infections R.J. Whitley and S. Stagno; neurological manifestations of infection with the human immunodeficiency viruses, B.K. Evans et al; viral vaccines that protect the central nervous system, M.F. Mangano and S.A. Plotkin; Guillain-Barre syndrome, G. Tenorio et al. Part 2 Mycoplasmal infections of the central nervous system: mycoplasmal diseases of the central nervous system, W.A. Clyde, Jr. Part 3 Bacterial infections of the central nervous system: pathogenesis and pathophysiology of bacterial infections of the central nervous system, A.R. Tunkel and W.M. Scheld; neonatal bacterial meningitis, A.L. Smith and J. Haas; acute bacterial meningitis in children and adults, K.L. Roos et al; rickettsiae and the central nervous system, J.H. Kim and D.T. Durack; tuberculosis of the central nervous system, A. Zuger and F.D. Lowy; brain abscess, B. Wispelwey et al; subdural empyema, D.C. Hefgott et al; epidural abscess, B.G. Gellin et al; central nervous system complications of infective endocarditis, P. Francioli; infections of the cerebrospinal fluid shunts, B.A. Kaufman and D.G. McLone. Part 4 Central nervous system syndromes mediated by bacterial toxins: botulism, J.M. Hughes; tetanus, T.P. Bleck; bordetella pertussis and the central nervous system, E.L. Hewlett. Part 5 Spriochetal infections of the central nervous system: central nervous system syphilis, E.W. Hook, III; Lyme disease, L. Reik, Jr. Part 6 Fungal infections of the central nervous system: pathogenesis and pathophysiology of fungal infections, J. R. Perfect and D.T. Durack; chronic meningitis, T. Tucker and J.J. Ellner; diagnosis and treatment of fungal meningitis, J.R. Perfect; space-occupying fungal lesions of the central nervous system, K. Sepkowitz and D. Armstrong. Part 7 Protozoal and helminthic infections of the central nervous system: protozoal infections, J.P. Cegielski and D.T. Durack; toxoplasmosis, C.S. Dukes et al; helminthic infections, M.L. Cameron and D.T. Durack.
