Jak-Stat Signaling: From Basics to Disease - Bookswagon UAE
Home > Science & Mathematics > Biology, life sciences > Microbiology (non-medical) > Jak-Stat Signaling: From Basics to Disease
Jak-Stat Signaling: From Basics to Disease

Jak-Stat Signaling: From Basics to Disease


     0     
5
4
3
2
1



International Edition


About the Book

The continuing fascination with Jaks and Stats: An introduction .- Regulation of JAKs: Insights gleaned from the functional protein domains .- Nuclear functions of the Janus Kinases .- Self-association of STAT proteins from monomers to paracrystals .- How Stats interact with the molecular machinery of transcriptional activation .- Nongenomic Functions of STAT3 .-Evolution of Jak and Stat proteins .- JAK/STAT and chromatin regulation in Drosophila . JAK/STAT signaling and invertebrate immune responses .- Stat5 as a hematopoietic master regulator for differentiation and neoplasia development .- Regulation of dendritic cell development by STATs .- STAT transcription factors - Controlling all aspects of NK cell biology .- Function of JAKs and STATs in lymphocytes: Bench to bedside .- The role of Janus kinases in hematopoietic malignancies .- Activation of Janus kinases during tumorigenesis . STAT1 and STAT3 transcription factors in inflammation-associated colon cancer .- Universal and specific functions of STAT3 in solid tumours .- Impact of STAT5 on normal tissue development and cancer .- Crosstalk with the Jak-STAT pathway in inflammation .- Activation and inhibition of JAK-STAT signal transduction by RNA viruses .- Multifaceted antiviral actions of interferon-stimulated gene products .- Interferon regulation of the innate response to bacteriaEvolution of Jak and Stat proteins .- JAK/STAT and chromatin regulation in Drosophila . JAK/STAT signaling and invertebrate immune responses .- Stat5 as a hematopoietic master regulator for differentiation and neoplasia development .- Regulation of dendritic cell development by STATs .- STAT transcription factors - Controlling all aspects of NK cell biology .- Function of JAKs and STATs in lymphocytes: Bench to bedside .- The role of Janus kinases in hematopoietic malignancies .- Activation of Janus kinases during tumorigenesis . STAT1 and STAT3 transcription factors in inflammation-associated colon cancer .- Universal and specific functions of STAT3 in solid tumours .- Impact of STAT5 on normal tissue development and cancer .- Crosstalk with the Jak-STAT pathway in inflammation .- Activation and inhibition of JAK-STAT signal transduction by RNA viruses .- Multifaceted antiviral actions of interferon-stimulated gene products .- Interferon regulation of the innate response to bacteria.


About the Author:

Thomas Decker obtained a masters degree in Biology and, in 1986, his PhD at the Albert-Ludwig University of Freiburg, Both his PhD project and his subsequent postdoctoral research at the Rockefeller University, New York, USA, concerned the immunological activity and molecular biology of interferons. This line of research led to intensive investigation of Jak-Stat signal transduction which continued duing subsequent group leader positions and professorships at the Fraunhofer Society, Hannover, Germany, the Karolinska Institute, Stockholm, Sweden and, finally, the University of Vienna where he currently holds the position of a full professor of immunobiology. Work in Decker's laboratory revolves around interferons, the Jak-Stat signalling pathway and mechanisms of gene activation in bacterial infections.

Mathias Müller studied veterinary medicine at the Ludwig-Maximilians University Munich (Germany) and completed his PhD thesis at the Gene Center Munich. During a postdoctoral fellowship at the ICRF (Imperial Cancer Research Fund, London UK; now CRUK, Cancer Research UK) he entered the field of interferon signal transduction and participated in the pioneering studies that led to the identification of the biological roles of Jaks and Stats by genetic complementation of cytokine signalling defective mutant cell lines. In 1998 he was appointed Full Professor of Veterinary Biotechnology and Molecular Genetics at the University of Veterinary Medicine Vienna. His laboratory focuses on the use of transgenic models for studying JAK-STAT signalling networks.


Best Sellers



Product Details
  • ISBN-13: 9783709117521
  • Publisher: Springer Verlag GmbH
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 450
  • Series Title: English
  • Weight: 698 gr
  • ISBN-10: 3709117526
  • Publisher Date: 18 Jul 2014
  • Edition: 2012 ed.
  • Language: English
  • Returnable: N
  • Spine Width: 24 mm
  • Width: 156 mm


Similar Products

Add Photo
Add Photo

Customer Reviews

REVIEWS      0     
Click Here To Be The First to Review this Product
Jak-Stat Signaling: From Basics to Disease
Springer Verlag GmbH -
Jak-Stat Signaling: From Basics to Disease
Writing guidlines
We want to publish your review, so please:
  • keep your review on the product. Review's that defame author's character will be rejected.
  • Keep your review focused on the product.
  • Avoid writing about customer service. contact us instead if you have issue requiring immediate attention.
  • Refrain from mentioning competitors or the specific price you paid for the product.
  • Do not include any personally identifiable information, such as full names.

Jak-Stat Signaling: From Basics to Disease

Required fields are marked with *

Review Title*
Review
    Add Photo Add up to 6 photos
    Would you recommend this product to a friend?
    Tag this Book Read more
    Does your review contain spoilers?
    What type of reader best describes you?
    I agree to the terms & conditions
    You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.

    CUSTOMER RATINGS AND REVIEWS AND QUESTIONS AND ANSWERS TERMS OF USE

    These Terms of Use govern your conduct associated with the Customer Ratings and Reviews and/or Questions and Answers service offered by Bookswagon (the "CRR Service").


    By submitting any content to Bookswagon, you guarantee that:
    • You are the sole author and owner of the intellectual property rights in the content;
    • All "moral rights" that you may have in such content have been voluntarily waived by you;
    • All content that you post is accurate;
    • You are at least 13 years old;
    • Use of the content you supply does not violate these Terms of Use and will not cause injury to any person or entity.
    You further agree that you may not submit any content:
    • That is known by you to be false, inaccurate or misleading;
    • That infringes any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
    • That violates any law, statute, ordinance or regulation (including, but not limited to, those governing, consumer protection, unfair competition, anti-discrimination or false advertising);
    • That is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased or offensive, unlawfully threatening or unlawfully harassing to any individual, partnership or corporation;
    • For which you were compensated or granted any consideration by any unapproved third party;
    • That includes any information that references other websites, addresses, email addresses, contact information or phone numbers;
    • That contains any computer viruses, worms or other potentially damaging computer programs or files.
    You agree to indemnify and hold Bookswagon (and its officers, directors, agents, subsidiaries, joint ventures, employees and third-party service providers, including but not limited to Bazaarvoice, Inc.), harmless from all claims, demands, and damages (actual and consequential) of every kind and nature, known and unknown including reasonable attorneys' fees, arising out of a breach of your representations and warranties set forth above, or your violation of any law or the rights of a third party.


    For any content that you submit, you grant Bookswagon a perpetual, irrevocable, royalty-free, transferable right and license to use, copy, modify, delete in its entirety, adapt, publish, translate, create derivative works from and/or sell, transfer, and/or distribute such content and/or incorporate such content into any form, medium or technology throughout the world without compensation to you. Additionally,  Bookswagon may transfer or share any personal information that you submit with its third-party service providers, including but not limited to Bazaarvoice, Inc. in accordance with  Privacy Policy


    All content that you submit may be used at Bookswagon's sole discretion. Bookswagon reserves the right to change, condense, withhold publication, remove or delete any content on Bookswagon's website that Bookswagon deems, in its sole discretion, to violate the content guidelines or any other provision of these Terms of Use.  Bookswagon does not guarantee that you will have any recourse through Bookswagon to edit or delete any content you have submitted. Ratings and written comments are generally posted within two to four business days. However, Bookswagon reserves the right to remove or to refuse to post any submission to the extent authorized by law. You acknowledge that you, not Bookswagon, are responsible for the contents of your submission. None of the content that you submit shall be subject to any obligation of confidence on the part of Bookswagon, its agents, subsidiaries, affiliates, partners or third party service providers (including but not limited to Bazaarvoice, Inc.)and their respective directors, officers and employees.

    Accept

    New Arrivals



    Inspired by your browsing history


    Your review has been submitted!

    You've already reviewed this product!