1. Developing Extrachromosomal Gene Expression Vector Technologies: An Overview
Richard Wade-Martins
2. High Capacity Extrachromosomal Gene Expression Vectors
Olivia Hibbitt and Richard Wade-Martins
3. Naturally Occurring Minichromosome Platforms in Chromosome Engineering: An Overview
Elena Raimondi
4. Chromosome Transfer Via Cell Fusion
Marianna Paulis
5. Insertional Engineering of Chromosomes with Sleeping Beauty Transposition: An Overview
Ivana Grabundzija, Zsuzsanna Izsvák, and Zoltán Ivics
6. Rodent Transgenesis Mediated by a Novel Hyperactive Sleeping Beauty Transposon System
Lajos Mátés
7. Construction and Use of a Bottom-Up HAC Vector for Transgene Expression
Masashi Ikeno and Nobutaka Suzuki
8. De novo Generation of Satellite DNA-Based Artificial Chromosomes by Induced Large-Scale Amplification
Erika Csonka
9. Downstream Bioengineering of ACE Chromosomes for Incorporation of Site-Specific Recombination Cassettes
Amy L. Greene and Edward L. Perkins
10. Chromosome Engineering with Lambda-Integrase Mediated Recombination System: The ACE System
Tünde Praznovszky
11. Dendrimer Mediated Transfer of Engineered Chromosomes
Robert L. Katona
12. Engineered Chromosomes in Transgenics
Peter Blazso, Ildiko Sinko, and Robert L. Katona
13. Transfer of Stem Cells Carrying Engineered Chromosomes with XY Clone Laser System
Ildiko Sinko and Robert L. Katona
14. Mammalian Artificial Chromosomes and Clinical Applications for Genetic Modification of Stem Cells: An Overview
Robert L. Katona, Sandra L. Vanderbyl, and Carl F.Perez
15. Engineered Mammalian Chromosomes in Cellular Protein Production: Future Prospects
Malcolm L. Kennard