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Mass Spectrometry in Metabolomics

Mass Spectrometry in Metabolomics


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About the Book

Part I. Historical and Methodology Overview

1. Overview: of Mass Spectrometry Based Metabolomics: Opportunities and Challenges

G. A. Nagana Gowda and Danijel Djukovic

Part II. Global LC-MS Based Metabolic Profiling

2. Global Metabolic Profiling using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Yunpeng Qi, Yunlong Song, Haiwei Gu, Guorong Fan, and Yifeng Chai

3. LC-MS Profiling to Link Metabolic and Phenotypic Diversity in Plant Mapping Populations

Camilla B. Hill, Antony Bacic, and Ute Roessner

4. Mitochondrial Metabolomics Using High-Resolution Fourier-Transform Mass Spectrometry

Young-Mi Go, Karan Uppal, Douglas I. Walker, ViLinh Tran, Lauriane Dury, Frederick H. Strobel, Hélène Baubichon-Cortay, Kurt D. Pennell, James R. Roede, and Dean P. Jones

5. Sample Preparation Methods for LC-MS Based Global Aqueous Metabolite Profiling

Antoni Beltran, Sara Samino, and Oscar Yanes

Part III. Global GC-MS and CE-MS Based Metabolic Profiling

6. Methods of Discovery-Based and Targeted Metabolite Analysis by Comprehensive Two-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry Detection

Luke C. Marney, Dr. Jamin C. Hoggard, Kristen J. Skogerboe, and Robert E. Synovec

7. Analysis of Mouse Liver Metabolites by GC×GC-TOF MS

Xue Shi, Xinmin Yin, and Xiang Zhang

8. Metabolite Fingerprinting by Capillary Electrophoresis-Mass Spectrometry

Antonia Garcia, Shama Naz, and Coral Barbas

Part IV. Isotope Labeling Methods

9. Quantitative Metabolomic Profiling using Dansylation Isotope Labeling and Liquid Chromatography Mass Spectrometry

Ruokun Zhou and Liang Li

10. Quantitative Analysis of Amino and Organic Acids by Methyl Chloroformate Derivatization and GC-MS/MS Analysis

Hans Fredrik Nyvold Kvitvang, Kåre A. Kristiansen, Stina K. Lien, and Per Bruheim

11. Stable Isotope Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS

Richard M. Higashi, Teresa W-M. Fan, Pawel K. Lorkiewicz, Hunter N.B. Moseley, and Andrew N. Lane

Part V. Targeted Aqueous Metabolite Profiling

12. Multiplexed, Quantitative and Targeted Metabolite Profiling by LC-MS/MRM

Ru Wei, Guodong Li, and Albert B. Seymour

Part VI. Lipid Profiling Methods

13. Multi-Dimensional Mass Spectrometry-Based Shotgun Lipidomics

Miao Wang and Xianlin Han

14. Comprehensive Quantitative Determination of PUFA-Related Bioactive Lipids for Functional Lipidomics using High Resolution Mass Spectrometry

Mojgan Masoodi and Dietrich A. Volmer

15. Ultra-Performance Liquid Chromatography Mass Spectrometry Targeted Profiling of Bile Acids: Application to Serum, Liver Tissue and Cultured Cells of Different Species

Juan Carlos García-Cañaveras, María Teresa Donato, and Agustín Lahoz

Part VII. Profiling Volatile Organic Compounds

16. Analysis of Volatile Organic Compounds in Exhaled Breath by Gas Chromatography-Mass Spectrometry combined with Chemometric Analysis

Jan W. Dallinga, Agnieszka Smolinska, and Frederik-Jan van Schooten

17. Headspace SPME-GC-MS Metabolomics Analysis of Urinary Volatile Organic Compounds (VOCs)

Shucha Zhang and Daniel Raftery

Part VIII. Profiling and Imaging using Atmospheric Sampling Methods


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Product Details
  • ISBN-13: 9781493953196
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Edition: Softcover reprint of the original 1st ed. 2014
  • Language: English
  • Returnable: Y
  • Spine Width: 20 mm
  • Weight: 707 gr
  • ISBN-10: 1493953192
  • Publisher Date: 23 Aug 2016
  • Binding: Paperback
  • Height: 254 mm
  • No of Pages: 360
  • Series Title: Methods in Molecular Biology
  • Sub Title: Methods and Protocols
  • Width: 178 mm


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