Part I: Designs, Principles, and Methods
1. Microelectrode Designs for Oxidase-Based Biosensors
Stéphane Marinesco and Olivier Frey
2. Microelectrode Array Fabrication and Optimization for Selective Neurochemical Detection
Kevin N. Hascup, Erin R. Hascup, O. Meagan Littrell, Jason M. Hinzman, Catherine E. Werner, Verda A. Davis, Jason J. Burmeister, Francois Pomerleau, Jorge E. Quintero, Peter Huettl, and Greg A. Gerhardt
3. The Advantage of Microelectrode Technologies for Measurement in Delicate Biological Environments Such as Brain Tissue
Andrea Jaquins-Gerstl and Adrian C. Michael
4. Hexacyanoferrates as Mediators for Microelectrode Biosensors
Faming Tian and Nicholas Dale
5. Enzyme Immobilization on Microelectrode Biosensors
Natalia Vasylieva and Stéphane Marinesco
6. Characterization of Polymer-Enzyme Composite Biosensors for Brain Monitoring In Vivo
Robert D. O'Neill
Part II: Case Studies
7. Monitoring Extracellular Glutamate in the Brain by Microdialysis and Microsensors
Si Qin, Miranda (van der Zeyden) Evering, Ngabi Wahono, Thomas I.F.H. Cremers, and Ben H.C. Westerink
8. Sub-Second Measurements of Glutamate and Other Neurotransmitter Signaling Using Enzyme-Based Ceramic Microelectrode Arrays
Erin R. Hascup, Kevin N. Hascup, Pooja M. Talauliker, David A. Price, Francois Pomerleau, Jorge E. Quintero, Peter Huettl, Alain Gratton, Ingrid Strömberg, and Greg A. Gerhardt
9. Regulation of Extracellular Concentrations of D-Serine in the Central Nervous System Revealed by D-Amino Acid Oxidase Microelectrode Biosensors
Pierre Pernot, Caroline Maucler, and Stéphane Marinesco
10. Measurement of Purine Release with Microelectrode Biosensors
Nicholas Dale
11. Glucose and Lactate Monitoring Across the Rat Sleep-Wake Cycle
Raymond Cespuglio, Larissa Netchiporouk, and Nataliya Shram
12. Forebrain Cholinergic Systems and Cognition: New Insights Based on Rapid Detection of Choline Spikes Using Enzyme-Based Biosensors
Vinay Parikh and Martin Sarter
Part III: The Future?
13. Carbon Nanotubes-Based Microelectrode (Bio)sensors
Paloma Yáñez-Sedeño, Lourdes Agüí, and José M. Pingarrón
14. Label-Free Affinity Biosensors Based on Electrochemical Impedance Spectroscopy
Nicole Jaffrezic-Renault
15. Aptamer-Based Electrochemical Biosensors for the Detection of Small Molecules and Plasma Proteins
Cassie Ho and Hua-Zhong Yu
16. Electrochemiluminescent Biosensors: Neuroscience Applications
Robert J. Forster and Tia E. Keyes
17. Molecularly Imprinted Polymers: Promising Advanced Materials for In Vivo Sensing
Samir Akhtar, Dan Fei, Farhan Mirza, Sergey Piletsky, Shenqi Wang, and Yi Ge
