Modellazione omologica insilico della proteina di rivestimento del Papaya ring spot virus
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Modellazione omologica insilico della proteina di rivestimento del Papaya ring spot virus

Modellazione omologica insilico della proteina di rivestimento del Papaya ring spot virus


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About the Book

In questo studio, la sequenza della proteina di rivestimento è stata analizzata e modellata per esplorare le proprietà e la struttura del Papaya leaf curl virus, del Papaya Mosaic virus e del Papaya ring spot virus-P & W. Poiché non sono disponibili informazioni strutturali per la maggior parte delle sequenze proteiche disponibili nella Protein Data Bank, negli ultimi anni i metodi computazionali per la previsione della struttura delle proteine hanno suscitato grande interesse. Sono state calcolate le proprietà fisico-chimiche della proteina in esame. Per tutti e quattro i ceppi di Papaya virus sono stati rilevati il valore medio di idropatia (GRAVY), il pI, il coefficiente di estinzione, l'indice alifatico e l'indice di instabilità. Questo supporta la proteina ad avere una migliore interazione con l'acqua. La modellazione dell'omologia è stata eseguita con PHYRE2, ModWebe Swiss Model tool. Il modello è stato convalidato utilizzando il software PROSESS, che ha fornito un diagramma di Ramachandran per il ceppo del Papaya virus. Lo studio può aiutare a comprendere la funzione della proteina, il numero e i tipi di epitopi, le porzioni immunogene e l'idoneità alla produzione di anticorpi, agli studi tassonomici, agli studi di valutazione e alla diagnostica del virus.


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Product Details
  • ISBN-13: 9786205650004
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edizioni Sapienza
  • Height: 229 mm
  • No of Pages: 72
  • Spine Width: 4 mm
  • Width: 152 mm
  • ISBN-10: 6205650002
  • Publisher Date: 30 Jan 2023
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Weight: 168 gr


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