Modulation of Presynaptic Calcium Channels

Foreword: Gary Stephens

Overview

1. Spatial and temporal regulation of Ca²⁺ channels; Sumiko Mochida

Interaction partners of calcium channels

2. Neuronal functions of auxiliary calcium channel subunits; Gerald Obermair and Bernd Flucher

3. Reciprocal regulation of neuronal calcium channels by synaptic proteins; Norbert Weiss and Gerald Zamponi

4. Molecular architecture of Ca²⁺ channel complexes organized by β subunits in presynaptic active zones; Akito Nakao, Mitsuru Hirano, Yoshinori Takada, Shigeki Kiyonaka and Yasuo Mori

5. Control of Ca_V2 calcium channels and neurosecretion by heterotrimeric G protein coupled receptors; Mark L. Jewell and Kevin P.M. Currie

6. Regulation of Ca_V2 channels by small GTPases; Pierre Charnet, Frédérique Scamps, Matthieu Rousset, Claudine Menard, Michel Bellis and Thierry Cens

7. Protein interaction partners of Ca_v2.3 R-type voltage-gated calcium channels; Maxine Dibué, Etienne E. Tevoufouet, Andreas Krieger, Alexandra Kiel, Dimitar Evdokimov, Thomas Galetin, Serdar Alpdogan, Isha Akhtar, Sabrina Scharf, Renate Clemens, Kayalvizhi Radhakrishnan, Jürgen Hescheler, Toni Schneider, Marcel A. Kamp

8. Voltage-gated calcium channel signaling to the nucleus; Michel Bellis, Thierry Cens, Claudine Menard, Pierre Charnet and Matthieu Rousset

9. Presynaptic Ca²⁺ influx and its modulation at auditory calyceal terminals; Holger Taschenberger, Kun-Han Lin and Shuwen Chang

10. Use of synthetic Ca²⁺ channel peptides to study presynaptic function; Giovanna Bucci, Sumiko Mochida and Gary Stephens

Calcium channel therapeutics

11. Impact of a loss-of-function P/Q type Ca²⁺ channel mutation on excitatory synaptic control of cerebellar Purkinje neurons; David Friel

12. Ca_V2.1 (P/Q) voltage activated Ca²⁺ channels and synaptic transmission in genetic and autoimmune diseases; Osvaldo Uchitel

13. Splicing and editing to customize Ca_V channel structures for optimal neural function; Hua Huang, Juejin Wang and Tuck Wah Soong

14. Presynaptic calcium channels as drug targets for pain; Edward Stevens and Peter Fox

15. Sensory pathway modulation by calcium channel a₂d₁ subunit; Chunyi Zhou and Z. David Luo

Index