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Mouse Models of Developmental Genetic Disease

Mouse Models of Developmental Genetic Disease


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About the Book

Approximately three percent of newborn humans have congenital anomalies with significant cosmetic and/or functional consequences. Much of our ability to understand what has gone awry in these birth defects rests with development of animal models for them; the mouse has emerged as the model organism of choice for these studies. This volume reviews mouse models of specific developmental genetic diseases, including neural tube defects; cleft lip and/or palate; congenital heart disease; ciliopathies; hereditary deafness and others to provide conceptual insight into congenital anomalies generally. The interplay between clinical observation and murine model systems is expected to yield deep insight into mammalian developmental processes and the emergence of effective preventive and/or therapeutic strategies.


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Product Details
  • ISBN-13: 9780123744548
  • Publisher: Academic Press
  • Publisher Imprint: Academic Press
  • Depth: 31
  • Height: 229 mm
  • No of Pages: 493
  • Series Title: Current Topics in Developmental Biology
  • Sub Title: Volume 84
  • Weight: 1137 gr
  • ISBN-10: 0123744547
  • Publisher Date: 15 Dec 2008
  • Binding: Hardback
  • Edition: 1
  • Language: English
  • Returnable: Y
  • Spine Width: 36 mm
  • Volume: 84
  • Width: 155 mm


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