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Multiplex Biomarker Techniques

Multiplex Biomarker Techniques


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About the Book

Part I: Reviews

1. Application of Multiplex Biomarker Approaches to Accelerate Drug Discovery and Development

Hassan Rahmoune and Paul C. Guest

2. The Application of Multiplex Biomarker Techniques for Improved Stratification and Treatment of Schizophrenia Patients

Johann Steiner, Paul C. Guest, Hassan Rahmoune, and Daniel Martins-de-Souza

3. Multiplex Biomarker Approaches in Type 2 Diabetes Mellitus Research

Susan E. Ozanne, Hassan Rahmoune, Daniel Martins-de Souza, and Paul C. Guest

4. LC-MSE, Multiplex MS/MS, Ion Mobility, and Label-Free Quantitation in Clinical Proteomics

Gustavo Henrique Martins Ferreira Souza, Paul C. Guest, and Daniel Martins-de-Souza

5. Phenotyping Multiple Subsets of Immune Cells In Situ in FFPE Tissue Sections: An Overview of Methodologies

James R. Mansfield

Part II: Statistical Considerations

6. Identification and Clinical Translation of Biomarker Signatures: Statistical Considerations

Emanuel Schwarz

7. Opportunities and Challenges of Multiplex Assays: A Machine Learning Perspective

Junfang Chen and Emanuel Schwarz

Part III: Protocols

8. Multiplex Analyses Using Real-Time Quantitative PCR

Steve F.C. Hawkins and Paul C. Guest

9. Multiplex Analysis Using cDNA Transcriptomic Profiling

Steve F.C. Hawkins and Paul C. Guest

10. Multiplex Single Nucleotide Polymorphism Analyses

Steve F.C. Hawkins and Paul C. Guest

11. Pulsed SILAC as a Proteomic Approach for miRNA Targets Identification in Cell Culture

Daniella E. Duque-Guimarães, Juliana de Almeida-Faria, Thomas Prates Ong, and Susan E. Ozanne

12. Blood Bio-Sampling Procedures for Multiplex Biomarkers Studies

Paul C. Guest and Hassan Rahmoune

13. Multiplex Immunoassay Profiling

Laurie Stephen

14. Multiplex Sequential Immunopreciptation of Insulin Secretory Granule Proteins from Radiolabeled Pancreatic Islets

Paul C. Guest

15. Two Dimensional Gel Electrophoresis of Insulin Secretory Granule Proteins from Biosynthetically-Labeled Pancreatic Islets

Paul C. Guest

16. Depletion of Highly Abundant Proteins of the Human Blood Plasma: Applications in Proteomics Studies of Psychiatric Disorders

Sheila Garcia, Paulo A. Baldasso, Paul C. Guest, and Daniel Martins-de-Souza

17. Simultaneous Two-Dimensio

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Product Details
  • ISBN-13: 9781493967292
  • Publisher: Humana Press
  • Publisher Imprint: Humana Press
  • Edition: 1st ed. 2017
  • Language: English
  • Returnable: Y
  • Spine Width: 19 mm
  • Weight: 847 gr
  • ISBN-10: 1493967290
  • Publisher Date: 29 Nov 2016
  • Binding: Hardback
  • Height: 254 mm
  • No of Pages: 317
  • Series Title: Methods in Molecular Biology
  • Sub Title: Methods and Applications
  • Width: 178 mm

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