Nano-patterning di superfici a-C
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Nano-patterning di superfici a-C

Nano-patterning di superfici a-C


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About the Book

Prevedere come le proteine si ripiegano e si adsorbono sulle superfici è un problema complesso di grande rilevanza per i settori della salute e dell'ambiente. Spesso viene esaminato nel contesto più ampio dell'adesione cellulare, ma la comprensione dell'adsorbimento delle proteine è complicata da molti fattori: il rilevamento cellulare e la segnalazione intercellulare, la topografia della superficie e il citoscheletro. Pertanto, gli studi sulle sole proteine sono preziosi per indagare la formazione di biofilm, le malattie da condensazione delle proteine e la tossicità dei nanomateriali. Questo libro presenta un'indagine sistematica sull'adsorbimento di proteine su film sottili di carbonio amorfo idrogenato (a-C: H). La prima metà tratta la preparazione e l'analisi dei pattern di a-C: H mediante fresatura a fascio ionico focalizzato (FIB) e nanoindentazione al microscopio a forza atomica (AFM). La seconda parte studia l'adsorbimento delle proteine per quattro diversi sistemi proteina/solvente. I risultati hanno dimostrato che le superfici modello nano-patternate sono utili per studiare e controllare l'adsorbimento delle proteine, mentre i metodi sviluppati possono essere estesi ad altre tecniche di patterning e a sistemi proteici per studiare in modo indipendente l'influenza della topografia e della composizione sull'adsorbimento delle proteine.


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Product Details
  • ISBN-13: 9786208198374
  • Publisher: KS Omniscriptum Publishing
  • Binding: Paperback
  • Language: Italian
  • Returnable: N
  • Sub Title: H per il controllo dell'adsorbimento di proteine
  • Width: 152 mm
  • ISBN-10: 6208198372
  • Publisher Date: 18 Oct 2024
  • Height: 229 mm
  • No of Pages: 104
  • Spine Width: 6 mm
  • Weight: 213 gr


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