New Rapid-Acting Antidepressants by Kenji Hashimoto
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New Rapid-Acting Antidepressants

New Rapid-Acting Antidepressants


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About the Book

​This book discusses new candidates for rapid-acting antidepressants, such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3 antagonists and AMPA receptor agonists. There are serious limitations to currently available antidepressants, such as delayed onset and low rates of efficacy. The discovery that a single dose of ketamine, an NMDAR antagonist, can produce rapid antidepressant effects that are sustained has led to new research in this area. In this volume, a variety of novel pharmaceutical treatments are examined. This volume would be useful to both researchers and clinicians who work in the field of pharmacology, specifically CNS drug treatments.

About the Author:

First Name - Kenji
Last Name - Hashimoto
Institution - Chiba University Center for Forensic Mental Health
Department - Division of Clinical Neuroscience
City - Chiba 260-8670
State - Chiba
Country - Japan
Email - hashimoto@faculty.chiba-u.jp


Kenji Hashimoto, PhD

Chiba University, Chiba, Japan

Dr. Hashimoto is a professor and vice-director of Chiba University Center for Forensic Mental Health from 2005. Dr. Hashimoto graduated from Faculty of Pharmaceutical Sciences at Kyushu University, and received PhD. After Dr. Hashimoto worked at Fukuyama University, National Institutes of Health (NIH)/National Institute of Drug Addiction (NIDA)(Baltimore, MD, USA) and Pharmaceutical company, he moved at Chiba University Graduate School of Medicine from 2001. Dr. Hashimoto works on the development of novel therapeutic drugs for psychiatric and neurological disorders. Dr. Hashimoto published more than 550 articles in PubMed listed publications. Dr. Hashimoto focus on the molecular and cellular mechanisms of ketamine's antidepressant actions.



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Product Details
  • ISBN-13: 9783030797928
  • Publisher: Springer International Publishing
  • Publisher Imprint: Springer
  • Height: 234 mm
  • No of Pages: 149
  • Spine Width: 9 mm
  • Width: 156 mm
  • ISBN-10: 3030797929
  • Publisher Date: 24 Oct 2022
  • Binding: Paperback
  • Language: English
  • Returnable: Y
  • Weight: 286 gr


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