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Next Generation Sequencing in Cancer Research

Next Generation Sequencing in Cancer Research


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About the Book

1. The evolution of high-throughput sequencing technologies: from Sanger to single molecule sequencing.....Chee-Seng Ku, Yudi Pawitan, Mengchu Wu, Dimitrios H. Roukos, David N. Cooper

2. Next generation sequencing in cancer epigenomics and potential clinical applications....Hong Kiat Ng, Dimitrios H. Roukos, Barry Iacopetta, Chee-Seng Ku

3. Next Generation Sequencing for Cancer Genomics.....Aarti N Desai and Abhay Jere

4. Genomic Landscape of Cancer Metastasis....Arvind Kumar Singla, Chandini Thirukkumaran and Wei Wu

5. Mapping the HIF transcription factor in cancer by ChIP-seq technology.....Johannes Schödel and David R. Mole

6. Application of next-generation sequencing to analysis of TGFβ/SMAD4 targets in ovarian cancer.....Russell Bonneville, Kenneth Nephew, and Victor X. Jin

7. Targeted Sequencing Strategies in Cancer Research.....HoJoon Lee, Billy T. Lau and Hanlee P. Ji

8. Comprehensive genomic alterations in common cancer cell lines revealed by exome-sequencing.....Han Chang, Donald G. Jackson, Paul S. Kayne, Petra B. Ross-Macdonald, Rolf-Peter Ryseck, and Nathan O. Siemers

9. Application of next generation sequencing in RNA biomarker discovery in cancer research.....Stephen P. Fink, and Kishore Guda

10. Understanding the role of long non-coding RNAs in the cancer genome.....Wei Wu and Jennifer A. Chan

11. Identification of piRNAs in HeLa cells by massive parallel sequencing.....Yilu Lu and Yongxin Ma

12. microRNA expression in breast cancer revealed by deep sequencing technology.....Thalia A. Farazi, Carl S. Leonhardt, and Thomas Tuschl

13. RNA-seq in prostate cancer research.....ShanCheng Ren, Min Qu, Yinghao Sun

14. Next-generation sequencing for high-throughput RNA interference screens.....Toby M. Ward, Anna-Maria Jegg, and Elizabeth Iorns

15. Assessment of Mapping and SNP-detection Algorithms for Next Generation Sequencing Data for Cancer Genomics.....Weixin Wang, Feng Xu, Junwen Wang

16. Applications of very low coverage sequencing in cancer genomics - copy number, virus detection and survival.....Henry M Wood

17. Tumor phylogenetics in the NGS era: Strategies, challenges and future prospects.....Ayshwarya Subramanian, Stanley Shackney and Russell Schwartz

18. Impact and challenges in assessing tumor purity by next-generation sequencing.....Xiaoping Su, Gabriel G. Malouf, and Francisco J. Esteva


About the Author: Wei Wu, M.D., Ph.D. is a Research Associate for the Department of Bio Science at the University of Calgary, specializing in the cancer genome and systems biology. He has edited two volumes with Springer. In addition, he's a member of various editorial board for journals including the International Journal of Biomedical Sciences, International Journal of Molecular Medicine and Advances in Sciences and the Research Journal of Biological Sciences. Hani Choudhry, D.Phil is a member of the Genomics Research Group at the Wellcome Trust Centre for Human Genetics at Oxford University. His expertise is in high throughput next generation sequencing.

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Product Details
  • ISBN-13: 9781489988089
  • Publisher: Springer
  • Publisher Imprint: Springer
  • Edition: Softcover reprint of the original 1st ed. 2013
  • Language: English
  • Returnable: N
  • Spine Width: 21 mm
  • Weight: 603 gr
  • ISBN-10: 1489988084
  • Publisher Date: 25 Aug 2015
  • Binding: Paperback
  • Height: 234 mm
  • No of Pages: 383
  • Series Title: English
  • Sub Title: Volume 1: Decoding the Cancer Genome
  • Width: 156 mm

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