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Notch Signaling in Embryology and Cancer

Notch Signaling in Embryology and Cancer


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International Edition


About the Book

1. Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling

2. Overview of Basic Mechanisms of Notch Signaling in Development and Disease

3. Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate

4. Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling

5. Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster

6. Molecular Regulation of Notch Signaling by Gremlin

7. Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex

8. Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss

9. Insulin-dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation

10. Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond

Index


About the Author:

Sandra and Jörg Reichrath are working at the Clinic for Dermatology; Allergology and Venerology of the Saarland University Hospital in Homburg/Saar. Germany. Main research interests include photobiology, carcinogenesis of skin cancer (with a special interest for the role of ultraviolet radiation, Notch and p53), and the relevance of the vitamin D endocrine system for health and disease. Sandra received her academic degrees (Dipl. Biol. and Dr. rer. nat.) from the Albert-Ludwigs-Universität (Freiburg, Germany) and from Saarland University (Saarbrücken/Homburg, Germany), respectively. Jörg received his academic degrees (Dr. med., venia legendi) from Saarland University (Saarbrücken/Homburg, Germany). He has been awarded numerous prizes including the Arnold-Rikli-Prize in 2006.


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Product Details
  • ISBN-13: 9783030364212
  • Publisher: Springer International Publishing
  • Publisher Imprint: Springer
  • Height: 254 mm
  • No of Pages: 172
  • Series Title: Advances in Experimental Medicine and Biology
  • Sub Title: Molecular Biology of Notch Signaling
  • Width: 178 mm
  • ISBN-10: 3030364216
  • Publisher Date: 19 Feb 2020
  • Binding: Hardback
  • Language: English
  • Returnable: Y
  • Spine Width: 13 mm
  • Weight: 598 gr


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