Nouvelles combinaisons thérapeutiques pour le traitement du cancer de la prostate
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Nouvelles combinaisons thérapeutiques pour le traitement du cancer de la prostate

Nouvelles combinaisons thérapeutiques pour le traitement du cancer de la prostate


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About the Book

Le cancer de la prostate est une maladie répandue chez les hommes. Il commence généralement par être androgéno-dépendant et évolue vers un phénotype androgéno-indépendant avec le temps. La CBG, un antagoniste connu des récepteurs de la sérotonine, peut avoir des effets pharmacologiques bénéfiques sur le développement des tumeurs androgéno-dépendantes. Il a été proposé que la DHEA, le dérivé éthanolamide de l'acide gras polyinsaturé DHA, soit plus efficace pour inhiber la croissance et la prolifération des cellules cancéreuses de la prostate que sa molécule mère. La lignée cellulaire LNCaP, sensible aux androgènes, a été utilisée pour un test de viabilité cellulaire in vitro dans le cadre de ce projet. L'objectif de l'étude était d'examiner les effets pharmacologiques de nouvelles combinaisons thérapeutiques dans le cancer de la prostate. Neuf combinaisons différentes de CBG et de DHEA ont été utilisées pour traiter les cellules. Sur la base d'une série d'analyses de données, les combinaisons 1:1 et 1:5 (avec un excès de DHEA) montrent un type d'interaction synergique prometteur. Ce travail devrait aider les chercheurs à établir l'effet précis des combinaisons médicamenteuses entre CBG et éthanolamides sur le cancer de la prostate.


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Product Details
  • ISBN-13: 9786207033447
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Editions Notre Savoir
  • Height: 229 mm
  • No of Pages: 52
  • Spine Width: 3 mm
  • Width: 152 mm
  • ISBN-10: 6207033442
  • Publisher Date: 14 Jan 2024
  • Binding: Paperback
  • Language: French
  • Returnable: N
  • Weight: 141 gr


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