Novas Combinações Antimaláricas para Paludismo Resistente à Cloroquina
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Novas Combinações Antimaláricas para Paludismo Resistente à Cloroquina

Novas Combinações Antimaláricas para Paludismo Resistente à Cloroquina


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About the Book

A malária aflige 300-500 milhões de pessoas no mundo e a mortalidade varia de 1-2 milhões, sendo as crianças na África as mais suscetíveis. Com uma vacina não disponível contra a malária e os medicamentos de primeira linha, como cloroquina e antifolatos, registrando resistência generalizada do parasita, o desafio do tratamento da malária é uma tarefa formidável. Se a pesquisa para descobrir novos medicamentos tornou-se essencial, também se tornou necessário identificar estratégias terapêuticas a curto prazo. Uma abordagem é examinar se medicamentos conhecidos usados ​​para outras aplicações podem ser usados ​​para tratar a malária. Uma segunda estratégia é procurar compostos naturais para atividade antimalárica isoladamente ou em combinação. A terapia combinada assumiu uma importância considerável no contexto dos derivados da artemisinina, sendo os únicos antimaláricos testados e eficazes deixados de lado. Uma terapia combinada com derivados de artemisinina pode prevenir a recrudescência devido à monoterapia, prolongar a vida útil da droga e talvez também reduzir o custo da terapia.


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Product Details
  • ISBN-13: 9786205773956
  • Publisher: KS Omniscriptum Publishing
  • Publisher Imprint: Edicoes Nosso Conhecimento
  • Height: 229 mm
  • No of Pages: 180
  • Spine Width: 10 mm
  • Width: 152 mm
  • ISBN-10: 6205773953
  • Publisher Date: 07 Mar 2023
  • Binding: Paperback
  • Language: Portuguese
  • Returnable: N
  • Weight: 322 gr


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