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The Origins of Genome Architecture

The Origins of Genome Architecture


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About the Book

With official genomic blueprints now available for hundreds of species, and thousands more expected in the near future, the field of biology has been forever transformed. Such readily accessible data have encouraged the proliferation of adaptive arguments for the evolution of gene and genomic
features, often with little or no attention being given to simpler and more powerful alternative explanations. By integrating the central observations from molecular biology and population genetics relevant to comparative genomics, Lynch shows why the details matter.

Presented in a nontechnical fashion, at both the population-genetic and molecular-genetic levels, this book offers a unifying explanatory framework for how the peculiar architectural diversity of eukaryotic genomes and genes came to arise. Under Lynch's hypothesis, the genome-wide repatterning of
eukaryotic gene structure, which resulted primarily from nonadaptive processes, provided an entirely novel resource from which natural selection could secondarily build new forms of organismal complexity.

About the Author:
Michael Lynch is Distinguished Professor of Biology at Indiana University. He received his B.S. in Biology from St. Bonaventure University, and his Ph.D. in Ecology from the University of Minnesota. Dr. Lynch has served as President of both the Society for the Study of Evolution and the American
Genetic Association, and is a past council member of the Society for Molecular Biology and Evolution, and a fellow of the American Academy of Arts and Sciences. His research is focused on mechanisms of evolution at the gene, genomic, cellular, and phenotypic levels, with special attention being
given to the roles of mutation, random genetic drift, and recombination.


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Product Details
  • ISBN-13: 9780878934843
  • Publisher: Sinauer Associates Is an Imprint of Oxford University Press
  • Publisher Imprint: Sinauer Associates Is an Imprint of Oxford University Press
  • Depth: 25
  • Height: 188 mm
  • No of Pages: 512
  • Series Title: English
  • Weight: 1160 gr
  • ISBN-10: 0878934847
  • Publisher Date: 03 Mar 2007
  • Binding: Hardback
  • Edition: 1
  • Language: English
  • Returnable: Y
  • Spine Width: 30 mm
  • Width: 246 mm


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