Pathology of Pediatric Gastrointestinal and Liver Disease

Ten years have elapsed since the printing of the second edition of this book. Since then there's been a veritable explosion of information coming mainly from the field of molecular diagnostics, which bear particular importance in the classification and treatment of Infantile enteropathies, disorders associated with immunodeficiencies, the classification of intestinal polyps and polyposis syndromes in childhood, cholestatic and metabolic disorders of childhood, liver tumors and transplantation pathology, all of which were major subjects explored in our previous editions. In this updated third edition, most of the chapters have been extensively revised to incorporate updated understanding in pathogenesis and terminology. For example, the widespread use of genetic panels and next generation sequencing in the diagnosis of cholestatic disorders of infancy and childhood, not widely available when the last edition was being prepared, prompted the writing of an entirely new chapter reflecting these advances by a new set of authors. Similarly, progress in diagnosis and classification of liver tumors justified an entirely new chapter on liver tumors that incorporates newer patient stratification in treatment protocols and reflects the new WHO classification of liver tumors. Pathology of Pediatric Gastrointestinal and Liver Disease 3rd Edition provides the pediatric pathologist, the GI or general pathologist, and the pediatric gastroenterologist with the most complete and current reference on the subject. It includes in-depth discussions on disorders and issues that are frequently encountered but for which up-to-date information is often not readily available, as well as infrequent disorders unique or specific to children that are not covered in standard texts.

Table of Contents:
Chapter 1. Developmental Anatomy and Anomalies of the Gastrointestinal Tract with Involvement in Major Malformative Syndromes.- Chapter 2. Esophageal Disorders of Childhood.- Chapter 3. Gastritis and gastropathies of Childhood.- Chapter 4. Enteropathies associated with Chronic diarrhea and malabsorption in Childhood.- Chapter 5. Gastrointestinal and hepatic involvement in immunodeficiencies and systemic disease of childhood.- Chapter 6. Colitis in Infancy and Childhood.- Chapter 7. Intestinal Motor Disorders.- Chapter 8. Polyps and Tumors of the Gastrointestinal Tract in Childhood.- Chapter 9. Normal and Abnormal Liver Development.- Chapter 10. Diseases of the Biliary Tree.- Chapter 11. Hepatocellular and Intrahepatic Cholestasis.- Chapter 12. Hepatitis and Liver Failure in Infancy and Childhood.- Chapter 13. The Liver in  Genetic Metabolic Disease.- Chapter 14. Hepatic Tumors in Childhood.- Chapter 15. GI and Liver Transplantation pathology in Childhood.